Results 141 to 150 of about 64,834 (257)

Appendiceal Gastrointestinal Stromal Tumor: A Case Report and Review of the Relevant Literature. [PDF]

Cureus
Maki T, Fujikawa T, Yamana I, Kinoshita I, Hasegawa S.   +4 more
europepmc   +1 more source

RUNX1‐Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells

Cancer Science, EarlyView.
RUNX1 transcriptionally activates CPXM1, promotes EMT, and enhances the proliferation, invasion, and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) remains a leading cause of cancer‐related mortality worldwide, with current treatment strategies largely limited to surgery, chemotherapy, and targeted therapy.
Ping Jia, Fengming Xu, Tao Zhou, Pingping Wang, Huiping Chen, Jing Zhang, Xiaochen Yuan, Haoxun Xu, Yu Ouyang   +8 more
wiley   +1 more source

Primary pulmonary gastrointestinal stromal tumor: A case report

Asian Journal of Surgery
Fang Ma, Xiuling Zhang, Fan Zhang, Lili Wang   +3 more
doaj   +1 more source

Jejunal Gastrointestinal Stromal Tumor Presenting as Life-Threatening Melena and Profound Anemia: A Case Report. [PDF]

Cureus
Ravella B, Gadde EC, Ravipati H, Pamatmat N.   +3 more
europepmc   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

Cancer Science, EarlyView.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

The effect of adjuvant imatinib treatment for patients with high-risk gastrointestinal stromal tumor. [PDF]

Front Oncol
Zhang J, Gao D, Cui H, Li J, Ao H, Wu X.
europepmc   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Gastrointestinal Stromal Tumor (GIST) Arising in the Setting of a Large Hiatal Hernia: A Case Report. [PDF]

Int Med Case Rep J
Maqul AH, Osman KA, Farah AA, Osman WA.
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Targeting tumor dormancy: the next frontier in gastrointestinal stromal tumor therapy. [PDF]

Neoplasia
Wu S, Liu H, Yin Y, Li J, Zhang Z, Li W, Fu Y.   +6 more
europepmc   +1 more source