Journal of Medical Case Reports, 2022 Background Neurofibromatosis type 1 is an inherited cancer predisposition syndrome that is caused by a mutation in the NF1 gene that encodes neurofibromin. Patients with neurofibromatosis type 1 have a higher risk of gastrointestinal stromal tumor.
B. G. Bharath +3 more
doaj +1 more source
A case of primary gastrointestinal stromal tumor of the liver
Radiology Case Reports, 2023 A gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. The tumor originates from Cajal cells, which generated peristaltic motion.
An Nguyen Thi My Xuan, MD +5 more
doaj +1 more source
Multifocal gastrointestinal stromal tumor with osseous metaplasia: a case report
Journal of Medical Case Reports, 2023 Background Gastrointestinal stromal tumor is considered the most common mesenchymal neoplasm of the gastrointestinal tract. The majority of gastrointestinal stromal tumor cases are located in the stomach and usually affects older adults.
Maryam Abdullah Al Saleem +2 more
doaj +1 more source
Duodenal Gastrointestinal Stromal Tumor
Journal of Clinical and Biomedical Sciences, 2019 Gastrointestinal stromal tumors (GIST) are nonepithelial tumors arising from the interstitial cells of Cajal. They express KIT protein-CD117 on immunohistochemistry.
Divya Teja Patil +3 more
doaj +1 more source
A large gastrointestinal stromal tumor of the duodenum treated by partial duodenectomy with Roux-en-Y duodenojejunostomy: a case report [PDF]
, 2013 INTRODUCTION: Duodenal gastrointestinal stromal tumors are uncommon and a relatively small subset of gastrointestinal stromal tumors whose optimal surgical procedure has not been well defined.
Abdelmalek Oussaden +5 more
core +1 more source
Unusual appearance of a pendulated gastric tumor : always think of GIST [PDF]
, 2012 Objective. To investigate the clinicopathological characteristics of gastrointestinal stromal tumor (GIST) with significant cystic changes and to assess the molecular genetic characteristics. Methods.
Anne Hoorens +5 more
core +4 more sources
Gastrointestinal Stromal Tumors [PDF]
Gastroenterology Clinics of North America, 2013 Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract. Soon after GIST was recognized as a tumor driven by a KIT or platelet-derived growth factor receptor mutation, it became the first solid tumor target for tyrosine kinase inhibitor therapies.
Markku, Miettinen, Jerzy, Lasota
openaire +2 more sources
Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience [PDF]
, 2019 Introduction. Gastrointestinal stromal tumors (GISTs) represent a rare type of gastrointestinal neoplasms. Resection with negative margins has been established as a mainstay treatment, but laparoscopic resections are still open to debate.
Alecu, Lucian +4 more
core +2 more sources
Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. [PDF]
, 2016 Gastrointestinal stromal tumors (GIST) arise within the interstitial cell of Cajal (ICC) lineage due to activating KIT/PDGFRA mutations. Both ICC and GIST possess primary cilia (PC), which coordinate PDGFRA and Hedgehog signaling, regulators of ...
Bardsley, Michael R +18 more
core +2 more sources
Cystic Esophageal Gastrointestinal Stromal Tumor (GIST): A Rare presentation
Journal of Bahria University Medical and Dental College, 2022 Gastrointestinal stromal tumors (GIST) are solid tumors of the gastrointestinal tract. The stomach is the most common site while the esophagus is the least common site for gastrointestinal stromal tumors.
Junaid Iqbal +3 more
doaj +1 more source