Results 231 to 240 of about 106,101 (300)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Targeted knockdown of canine KIT (stem cell factor receptor) using small interfering RNA [PDF]

open access: yes, 2010
Argyle, D.   +3 more
core  

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen   +7 more
wiley   +1 more source

Macro Habitat‐Based T2‐Weighted MRI Radiomics and Deep Learning Fusion for Predicting Treatment Response and Prognosis After Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced rectal cancer (LARC) is highly heterogeneous. Reliable pretreatment prediction of tumor regression and prognosis remains an unmet clinical need to optimize personalized management.
Xiaoli Jin   +7 more
wiley   +1 more source

Multi‐Transcriptomic Analysis Reveals That EREG‐Driven TME Crosstalk Defines Anti‐EGFR Response in Colorectal Cancer

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
A multi‐transcriptomic analysis reveals the “EREG/EGFR/CSF axis” as a key intercellular network in the tumor microenvironment that dictates anti‐EGFR sensitivity in colorectal cancer. ABSTRACT Sidedness influences colorectal cancer (CRC) prognosis and treatment response, yet the mechanism dictating differential EGFR inhibitor (EGFRI) sensitivity is ...
Atsuki Taniguchi   +9 more
wiley   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang   +4 more
wiley   +1 more source

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