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Nutrition and the gastrointestinal tract [PDF]
In this year’s issue, we again have a high-calibre collection of topical reviews. Gracie and Ford commence with an assessment of the role of symbiotics (i.e. probiotics and prebiotics given together) in patients with irritable bowel syndrome.
Correia, M. Isabel T.D.+1 more
core +5 more sources
Background Upper extremity deep vein thrombosis (UEDVT) is relatively rare but cannot be negligible because it can cause fatal complications. Although it is reported that the occurrence rate of UEDVT has increased due to central venous catheter (CVC ...
Leo Yamada+22 more
doaj +1 more source
Background Systemic inflammation has been reported to be associated with cancer progression and metastasis. Systemic inflammation score (SIS), calculated from preoperative serum albumin level and lymphocyte-to-monocyte ratio, has been shown to be a novel
Takuro Matsumoto+14 more
doaj +1 more source
Functional benefits of the double flap technique after proximal gastrectomy for gastric cancer
Background Proximal gastrectomy is a widely performed procedure that has become more common with an increasing number of proximal gastric cancer cases.
Zenichiro Saze+9 more
doaj +1 more source
Objectives: The standard strategy for advanced rectal cancer (RC) is preoperative short-course radiotherapy (SCRT)/chemoradiotherapy (CRT) plus total mesorectal excision (TME) in Western countries; however, the survival benefit of adding chemotherapy to ...
Wataru Sakamoto+10 more
doaj +1 more source
Trastuzumab deruxtecan (T-DXd), a HER2-targeting antibody–drug conjugate with a topoisomerase I inhibitor deruxtecan (DXd), exhibits an excellent anti-tumor effect in previously treated HER2-positive tumors.
Shotaro Nakajima+15 more
doaj +1 more source
Epstein-Barr virus-positive gastric cancer [EBV (+) GC] is a distinct GC subtype with unique genetic and epigenetic aberrations. Here, we examined resected GC samples and publicly available microarray data and The Cancer Genome Atlas (TCGA) database to ...
Hiroshi Nakano+18 more
doaj +1 more source
Metformin and the gastrointestinal tract [PDF]
Metformin is an effective agent with a good safety profile that is widely used as a first-line treatment for type 2 diabetes, yet its mechanisms of action and variability in terms of efficacy and side effects remain poorly understood. Although the liver is recognised as a major site of metformin pharmacodynamics, recent evidence also implicates the gut
McCreight, Laura J.+2 more
openaire +5 more sources
Microbiota in the Gastrointestinal Tract [PDF]
Gut microbiota are permanent residents of humans with the highest concentrations being found in human colon. Humans get the first contact with bacteria at delivery, and microbiota are subject of permanent change during the life. The individual microbiota pattern is highly variable and varying environmental conditions, e.g., diets, antigen exposure ...
Walburga Dieterich+2 more
openaire +5 more sources
Adenocarcinoma of the gastroesophageal junction (AEG) has become increasingly common in Western and Asian populations. Surgical resection is the mainstay of treatment for AEG; however, determining the distance from the upper edge of the tumor to the ...
Tao Pang, Mingming Nie, Kai Yin
doaj +1 more source