Results 31 to 40 of about 613,558 (366)

Effect of fermented feed on the microbial population of the gastrointestinal tracts of pigs

, 2001
An in vivo experiment was performed with pigs to study the inhibitory effect of fermented feed on the bacterial population of the gastrointestinal tract.
Lipman, L.J.A., Verheijden, J.H.M., van Winsen, R.L., Urlings, B.A.P., Knapen, F., van, van Knapen, F., Winsen, R.L., van, Keuzenkamp, D., Snijders, J.M.A.   +8 more
core   +1 more source

The host genotype affects the bacterial community in the human gastrointestinal tract

, 2001
The gastrointestinal (GI) tract is one of the most complex ecosystems consisting of microbial and host cells. It is suggested that the host genotype, the physiology of the host and environmental factors affect the composition and function of the ...
Vos, W.M., de, Visser, J.A.G.M., de, Zoetendal, E.G., Akkermans, A.D.L., Akkermans-van Vliet, W.M.   +4 more
core   +1 more source

Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]

, 2012
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
Allsopp Philip, Magee Pamela, González-Barrio, Rocio, Rocio González-Barrio (117854), McDougall, Gordon J., Gill, Chris I. R., Philip Allsopp (117857), Ian Rowland (117868), Gordon J. McDougall (117848), Gema Pereira-Caro (117851), Derek Stewart, Gema Pereira-Caro, McDougall Gordon J., Crozier Alan, Magee, Pamela, McDougall, G.J., Pamela Magee (117861), Philip Allsopp, Pamela Magee, Stewart Derek, Gordon J McDougall, Pereira-Caro, Gema, Gill Chris I. R., Stewart, D., Ian Rowland, Brown, E.M., Alan Crozier (117865), Brown Emma M., Gill, C.I.R., Pereira-Caro Gema, Derek Stewart (117849), Stewart, Derek, González-Barrio, R., Rowland, Ian, Pereira Caro, G., Emma M. Brown (117847), Rowland Ian, Rocio González-Barrio, Chris I R Gill, Pereira-Caro, G., Alan Crozier, Magee, P., Allsopp, P., González-Barrio, R, Crozier, A., Rowland, I., González-Barrio Rocio, Allsopp, Philip, Emma M Brown, Chris I. R. Gill (117871), Brown, Emma M., Crozier, Alan   +51 more
core   +1 more source

Metformin and the gastrointestinal tract [PDF]

Diabetologia, 2016
Metformin is an effective agent with a good safety profile that is widely used as a first-line treatment for type 2 diabetes, yet its mechanisms of action and variability in terms of efficacy and side effects remain poorly understood. Although the liver is recognised as a major site of metformin pharmacodynamics, recent evidence also implicates the gut
McCreight, Laura J., Bailey, Clifford J., Pearson, Ewan R.   +2 more
openaire   +4 more sources

An investigation of horizontal transfer of feed introduced DNA to the aerobic microbiota of the gastrointestinal tract of rats

, 2012
BACKGROUND: Horizontal gene transfer through natural transformation of members of the microbiota of the lower gastrointestinal tract (GIT) of mammals has not yet been described.
Raddadi Noura, Nielsen KM, Traavik T, Terje Traavik, Brusetti Lorenzo, Averhoff, Beate, Nordgård Lise, Beate Averhoff, Nordgård, Lise, Noura Raddadi, Brusetti L, Nielsen, Kaare Magne, Kaare Magne Nielsen, Traavik, Terje, Nielsen Kaare, Traavik Terje, Lorenzo Brusetti, Raddadi, Noura, Averhoff B, Brusetti, Lorenzo, Averhoff Beate, Nordgård L, Lise Nordgard   +22 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Applications of intraoperative ultrasound in the treatment of complicated cases of acute and chronic pancreatitis and pancreatic cancer – own experience

Journal of Ultrasonography, 2015
Both acute and chronic inflammation of the pancreas often lead to complications that nowadays can be resolved using endoscopic and surgical procedures. In many cases, intraoperative ultrasound examination (IOUS) enables correct assessment of the extent
Grzegorz Ćwik, Michał Solecki, Grzegorz Wallner   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8+ T cells in dMMR/MSI-H gastric cancer

Scientific Reports
Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) gastric cancer (GC) exhibits an immune-active tumor microenvironment (TME) compared to MMR proficient (pMMR)/microsatellite stable/Epstein-Barr virus-negative [EBV (−)] GC.
Ryo Kanoda, Shotaro Nakajima, Satoshi Fukai, Motonobu Saito, Katsuharu Saito, Hiroya Suzuki, Tomohiro Kikuchi, Azuma Nirei, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono   +14 more
doaj   +1 more source