Results 11 to 20 of about 1,251,513 (308)

High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota [PDF]

, 2008
The human gastrointestinal (GI) tract microbiota plays a pivotal role in our health. For more than a decade a major input for describing the diversity of the GI tract microbiota has been derived from the application of small subunit ribosomal RNA (SSU ...
Vos, W.M., de, de Vos, Willem M., Zoetendal, Erwin G., Rajilic-Stojanovic, M., Zoetendal, E.G., Rajilić-Stojanović, Mirjana   +5 more
core   +1 more source

Adjuvant SOX chemotherapy versus concurrent chemoradiotherapy after D2 radical resection of locally advanced esophagogastric junction (EGJ) adenocarcinoma: study protocol for a randomized phase III trial (ARTEG)

Trials, 2021
Background Survival benefit of adjuvant radiotherapy for locally advanced gastric cancer following gastrectomy plus D2 lymphadenectomy has always been controversial.
Jinwen Shen, Xiu Zhu, Yian Du, Yuan Zhu, Pengfei Yu, Litao Yang, Zhiyuan Xu, Ling Huang, Yunli Zhang, Yanqiang Zhang, Luying Liu, Xiangdong Cheng   +11 more
doaj   +1 more source

The host genotype affects the bacterial community in the human gastrointestinal tract [PDF]

, 2001
The gastrointestinal (GI) tract is one of the most complex ecosystems consisting of microbial and host cells. It is suggested that the host genotype, the physiology of the host and environmental factors affect the composition and function of the ...
Vos, W.M., de, Visser, J.A.G.M., de, Zoetendal, E.G., Akkermans, A.D.L., Akkermans-van Vliet, W.M., null Erwin G. Zoetendal, Antoon D. L. Ak   +5 more
core   +1 more source

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract [PDF]

, 2012
Background: G protein-coupled receptors (GPCRs) represent one of the largest families of transmembrane receptors and the most common drug target. The Adhesion subfamily is the second largest one of GPCRs and its several members are known to mediate ...
Schiöth, Helgi B,, Olszewski, Pawel K, Cedernaes, Jonathan,, Vergoni, Anna V, Schiöth, Helgi B, Jonathan Cedernaes, Schiöth, Helgi B., Anna V Vergoni, Pawel K Olszewski, Badiali, Luca, Luca Badiali, Olof Nylander, Badiali, Luca,, Helgi B Schiöth, Nylander, Olof, Nylander, Olof,, VERGONI, Anna Valeria, Olszewski, Pawel K., Vergoni, Anna V., Cedernaes, Jonathan, Olszewski, Pawel K,, Nylander Olof, Badiali Luca, Vergoni Anna V, Schiöth Helgi B, Olszewski Pawel K, Cedernaes Jonathan   +26 more
core   +2 more sources

Phase I/II clinical trial of nivolumab in combination with oligo-fractionated irradiation for unresectable advanced or recurrent gastric cancer

Communications Medicine, 2023
Background Although immune checkpoint inhibitors (ICI) targeting for PD-1 axis is a promising approach for advanced gastric cancer (GC) patients, the response rate is still limited.
Kosaku Mimura, Takashi Ogata, Yuya Yoshimoto, Daisaku Yoshida, Shotaro Nakajima, Hisashi Sato, Nozomu Machida, Takanobu Yamada, Yohei Watanabe, Tomoaki Tamaki, Hirohito Fujikawa, Yasuhiro Inokuchi, Suguru Hayase, Hiroyuki Hanayama, Zenichiro Saze, Hiroyuki Katoh, Fumiaki Takahashi, Takashi Oshima, Yoshiyuki Suzuki, Koji Kono   +19 more
doaj   +1 more source

Systemic sclerosis and the gastrointestinal tract [PDF]

, 2017
Systemic sclerosis (SSc) is an autoimmunological disease of unknown origin with complex pathogenesis and multiple organ involvement. It is characterised by vascular and immunological abnormalities leading to fibrosis of the skin and internal organs.
Irena Walecka
core   +1 more source

Risk factors for early and late morbidity in patients with cardiovascular disease undergoing inguinal hernia repair with a tailored approach: a single-center cohort study

BMC Surgery, 2023
Background Inguinal hernia repair is a common procedure in surgery. Patients with cardiovascular disease have an increased operative risk for postoperative morbidity.
Kamran Hajili, Alberto Vega Hernandez, Jakob Otten, Dana Richards, Claudia Rudroff   +4 more
doaj   +1 more source

Vasculitides of the gastrointestinal tract

Seminars in Diagnostic Pathology, 2009
Systemic vasculitis is often not considered as a possible diagnosis by clinicians because of its low prevalence compared with other more common diseases. Vasculitis can affect any end organ, and it is therefore often missed early on in disease progression.
Ahn, E, Luk, A, Chetty, R, Butany, J
openaire   +3 more sources

Protein degradation technology: a strategic paradigm shift in drug discovery

Journal of Hematology & Oncology, 2021
Targeting pathogenic proteins with small-molecule inhibitors (SMIs) has become a widely used strategy for treating malignant tumors. However, most intracellular proteins have been proven to be undruggable due to a lack of active sites, leading to a ...
Haobin Li, Jinyun Dong, Maohua Cai, Zhiyuan Xu, Xiang-Dong Cheng, Jiang-Jiang Qin   +5 more
doaj   +1 more source

Radiological findings spectrum of asymptomatic coronavirus (COVID-19) patients

The Egyptian Journal of Radiology and Nuclear Medicine, 2020
Background Radiological examinations of COVID-19 positive patients play a vital role in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns ...
Rasha Mostafa Mohamed Ali, Mai Bahgat Ibrahim Ghonimy   +1 more
doaj   +1 more source