Results 101 to 110 of about 5,047 (245)

Exploring gastroprotective effect and mechanisms of epigallocatechin gallate‐impregnated black garlic in acidic ethanol‐induced gastric ulcer model mice

Journal of the Science of Food and Agriculture, Volume 105, Issue 15, Page 8717-8732, December 2025.
Abstract Background Peptic ulcers, particularly gastric ulcers (GUs), are multifactorial disorders with unclear mechanisms. Black garlic (BG) has shown gastroprotective effects. This study evaluated the effects of BG and epigallocatechin gallate‐impregnated BG (EG) in acidic ethanol (AE)‐induced GU model mice. Mice were pretreated with BG or EG (50–200 
Ming‐Shiun Tsai, Gunn‐Guang Liou, Chang‐Wei Hsieh, Jiunn‐Wang Liao, Pin‐Yen Lai, Chao‐Kai Chang, Wan‐Jou Lee, Sue‐Hong Wang   +7 more
wiley   +1 more source

Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink [PDF]

, 2015
Study question: What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices?
Akbarov, Artur, Ashcroft, Darren M., Avery, Anthony J., Kontopantelis, Evangelos, Rodgers, Sarah, Stocks, S. Jill   +5 more
core   +1 more source

Quality of Co-Prescribing NSAID and Gastroprotective Medications for Elders in The Netherlands and Its Association with the Electronic Medical Record. [PDF]

PLoS ONE, 2015
To assess guideline adherence of co-prescribing NSAID and gastroprotective medications for elders in general practice over time, and investigate its potential association with the electronic medical record (EMR) system brand used.We included patients 65 ...
Dedan Opondo, Stefan Visscher, Saeid Eslami, Robert A Verheij, Joke C Korevaar, Ameen Abu-Hanna   +5 more
doaj   +1 more source

Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population‐Based Study

Fundamental &Clinical Pharmacology, Volume 39, Issue 6, December 2025.
ABSTRACT Background Direct‐acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population‐level impact on health outcomes and costs remains unclear. We examined whether the widespread uptake of DOACs was associated with changes in hospitalization rates and costs for ...
Tony Antoniou, Daniel McCormack, Tianru Wang, Mina Tadrous, Tara Gomes   +4 more
wiley   +1 more source

Preventive Gastroprotective Effect of a Functional Food Based on Quinoa (Chenopodium quinoa Willd.) and Quercetin in a Murine Model of Ibuprofen-Induced Gastric Damage

Antioxidants
Nonsteroidal anti-inflammatory drug-based therapies are the cause of 20–30% cases of gastric lesions in chronic users worldwide. Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of
Maribel Valenzuela-González, José Luis Cárdenas-López, Armando Burgos-Hernández, Norma Julieta Salazar-López, Manuel Viuda-Martos, Mónica A. Villegas-Ochoa, Gustavo Martínez-Coronilla, J. Abraham Domínguez-Avila, Shela Gorinstein, Gustavo A. González-Aguilar, Rosario Maribel Robles-Sánchez   +10 more
doaj   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, Volume 80, Issue 11, Page 2973-2987, November 2025.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

Developing a complex intervention to improve prescribing safety in primary care:mixed methods feasibility and optimisation pilot study [PDF]

, 2014
Objectives (A) To measure the extent to which different candidate outcome measures identified high-risk prescribing that is potentially changeable by the data-driven quality improvement in primary care (DQIP) intervention.(B) To explore the value of ...
Dreischulte, Tobias, Grant, Aileen M., Guthrie, Bruce   +2 more
core   +7 more sources

Ethanol extract of Argyreia acuta leaves attenuates NSAID-induced gastric inflammation in mice via antioxidant and immunomodulatory mechanisms

Notulae Scientia Biologicae
Indomethacin, a widely used NSAID, induces gastric injury via prostaglandin depletion, oxidative stress, and immune imbalance. This study evaluated the gastroprotective effects of Argyreia acuta leaf ethanol extract (EEAAL) in a murine model of ...
Tran Thi Phuong NHUNG, Le Pham Tan QUOC, Tran Thi HIEN   +2 more
doaj   +1 more source

Proton pump inhibitors: are they overutilised in clinical practice and do they pose significant risk? [PDF]

, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92027/1/j.1742-1241.2012.02921.x ...
American Society of Health-System Pharmacists, Aseeri, Batuwitage, Bhatt, Cash, Chiu, Conrad, Corley, de, DeVault, Dial, Dial, Dial, Fendrick, Forgacs, Gilard, Gillen, Gillen, Gray, Gulmez, Heidelbaugh, Heidelbaugh, Heidelbaugh, Howden, Hunfeld, Inadomi, Inadomi, Inadomi, Jacobson, Jayatilaka, Kahrilas, Kahrilas, Kaye, Klinkenberg-Knol, Klinkenberg-Knol, Laheij, Leonard, Mat Saad, Metz, Metz, Metz, Metz, Metz, Nardino, Naunton, Niklasson, Pisegna, Pouwels, Ray, Reimer, Robertson, Sachs, Sarkar, Scheiman, Schubert, Shi, Shin, Siller-Matula, Small, Targownik, Targownik, Van Soest, Vestergaard, Waldum, Yang, Yang, Yang, Yearsley, Zink   +68 more
core   +1 more source

A novel gastroprotective agent Osajin

, 2016
A NOVEL GASTROPROTECTIVE AGENT ...
HAMZAOĞLU, ERGİN, CAKIR, AHMET, DILEK, ESRA, KOÇ, MURAT, EROL, Hüseyin Serkan, HALICI, Mesut Bünyami   +5 more
openaire   +6 more sources