Results 81 to 90 of about 2,582 (208)

The gastroprotective role of yellow kepok Banana (Musa x Paradisiaca L. Var. Kepok) peel extract and influence on markers of oxidative stress: Malondialdehyde and nitric oxide [PDF]

Scripta Medica, 2023
Background/Aim: Flavonoids, tannins, saponins and polyphenols in yellow kepok banana (Musa x paradisiaca L. var. kepok) peel potentially could be a solution for peptic ulcer prevention.
Samiasih Amin, Khoiriyah Khoiriyah, Norma Ethica Stalis, Rahmawati Sulistyaningtyas Ayu, Pranata Satriya, Rino Vanchapo Antonius   +5 more
doaj  

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Traditional medicine and gastroprotective crude drugs

Journal of Ethnopharmacology, 2005
A frequent question when dealing with the search for gastroprotective compounds from natural sources is how far or close are both the plant preparations and extract amounts from the doses recommended in traditional medicine and what should be considered realistic levels for experimental studies. The administration way is oral and therefore extracts and
Schmeda-Hirschmann, G., Yesilada, E.
openaire   +6 more sources

Proton Pump Inhibitors Prescribing Behaviors and Rationalization Strategies Among Healthcare Providers in Southeast Asia

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Long‐term proton pump inhibitor (PPI) therapy raises significant concerns regarding cost‐effectiveness and adverse effects, necessitating effective deprescribing strategies. An evaluation of 763 Southeast Asian healthcare providers revealed two distinct prescriber phenotypes, where a proactive cluster utilized diverse, guideline‐based rationalization ...
Duc Trong Quach, Tien Manh Huynh, Augusto Jose G. Galang, Hang Viet Dao, Sakkarin Chirapongsathorn, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Andrew Ming‐Liang Ong, Wee Kooi Cheah, Kalwinder Singh Khaira, So Fie Tan, Jose Sollano, Ari Fahrial Syam, Tju Siang Chua, Somchai Leelakusolvong, Yeong Yeh Lee   +15 more
wiley   +1 more source

Protocol for the effective feedback to improve primary care prescribing safety (EFIPPS) study : a cluster randomised controlled trial using ePrescribing data [PDF]

, 2012
High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions to improve care are attractive because they are relatively cheap to widely implement. There is good evidence that feedback has small to moderate effects,
Barnett, Karen; id_orcid, Guthrie, Bruce, Petrie, D, Treweek, S, Robertson, C, Bennie, M, Barnett, K, Petrie, Dennis, Barnett, Karen, Ritchie, Lewis, Ritchie, Lewis D, Guthrie, B, Robertson, Chris, Bennie, Marion, Ritchie, LD, Treweek, S., Treweek, Shaun, Ritchie, Lewis D.   +17 more
core   +2 more sources

Preventive Gastroprotective Effect of a Functional Food Based on Quinoa (Chenopodium quinoa Willd.) and Quercetin in a Murine Model of Ibuprofen-Induced Gastric Damage

Antioxidants
Nonsteroidal anti-inflammatory drug-based therapies are the cause of 20–30% cases of gastric lesions in chronic users worldwide. Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of
Maribel Valenzuela-González, José Luis Cárdenas-López, Armando Burgos-Hernández, Norma Julieta Salazar-López, Manuel Viuda-Martos, Mónica A. Villegas-Ochoa, Gustavo Martínez-Coronilla, J. Abraham Domínguez-Avila, Shela Gorinstein, Gustavo A. González-Aguilar, Rosario Maribel Robles-Sánchez   +10 more
doaj   +1 more source

Dillapiole, Isolated from Peperomia pellucida, Shows Gastroprotector Activity against Ethanol-Induced Gastric Lesions in Wistar Rats

Molecules, 2013
Peperomia pellucida is a plant used in traditional medicine to treat gastric ulcers. Although this gastroprotective activity was reported, the active compounds have not been identified.
María Elena Sánchez-Mendoza, Antonio Magdiel Velázquez-Méndez, Daniel Arrieta-Baez, Leticia Cruz-Antonio, Jesús Arrieta, Raúl Rojas-Martínez   +5 more
doaj   +1 more source

Gastroprotective Effects of Hexanic Extract of the Leaves of Spondias purpurea and Its Underlying Mechanism of Action

Journal of Food Process Engineering, Volume 49, Issue 6, June 2026.
Histopathological analysis of gastric mucosa stained with HE and PAS of rats submitted to induction of ulcers with acetic acid. The animals were treated orally with vehicle (injured control), ranitidine, and SpHE (25 mg/kg) for 14 days. In A and B, observe preserved mucosa and submucosal layers (black asterisk) and presence of the barrier protection of
Cynthia Layse Ferreira de Almeida, Samara Alves Brito, Temístocles Italo de Santana, Henrique Alves Bandeira Alves Costa, Caroline Leal Rodrigues Soares, Natalie Emanuelle Ribeiro Rodrigues, Vanda Lucia dos Santos, Almir Gonçalves Wanderley, Henrique D. M. Coutinho, Teresinha Gonçalves da Silva   +9 more
wiley   +1 more source

Noncompliance with guidelines on proton pump inhibitor prescription as gastroprotection in hospitalized surgical patients who are prescribed NSAIDs [PDF]

, 2016
Background and aims As NSAIDs can cause serious upper gastrointestinal harm, guidelines have been established for the prescribing of proton pump inhibitors (PPIs) in high-risk patients using NSAIDs.
Verhofstad, Michiel; id_orcid, Esther M.M. van Lieshout, Verhofstad, Michiel, Verhofstad, M.H.J. (Michiel), Van Lieshout, Esther M.M.; id_orcid, Bemt, P.M.L.A. (Patricia) van den, Michael H.J. Verhofstad, Chaaouit, N, Naoual Chaaouit, van den Bemt, Patricia, Chaaouit, N. (Naoual), Van Lieshout, Esther M.M., Lieshout, E.M.M. (Esther) van, Patricia M.L.A. van den Bemt   +13 more
core   +2 more sources

Determination of candidates for adjunctive 'gastroprotective' prostaglandins [PDF]

The Journal of the American Osteopathic Association, 1990
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is now recognized as being frequently associated with asymptomatic gastric ulceration and its complications. Such adverse effects on the gastric mucosa have recently been found to occur with even greater frequency in certain NSAID-treated patients.
openaire   +2 more sources