Results 81 to 90 of about 2,310 (209)
Nonsteroidal anti-inflammatory drug-based therapies are the cause of 20–30% cases of gastric lesions in chronic users worldwide. Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of
Maribel Valenzuela-González +10 more
doaj +1 more source
Recommendation for gastroprotection in gastrointestinal bleeding prevention
Incidence of gastrointestinal bleeding in most populations is about 1 per 1,000 inhabitants. More than 65% of all bleeding episodes are associated with drug use. The most often involved are non-steroidal antiinflammatory drugs and low doses of acetyl-salicylic acid. The mortality within the first month after the bleeding episode is about 10-
Nemanja Damjanov +5 more
openaire +4 more sources
Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva +9 more
wiley +1 more source
Indomethacin, a widely used NSAID, induces gastric injury via prostaglandin depletion, oxidative stress, and immune imbalance. This study evaluated the gastroprotective effects of Argyreia acuta leaf ethanol extract (EEAAL) in a murine model of ...
Tran Thi Phuong NHUNG +2 more
doaj +1 more source
Glucocorticoids are gastroprotective under physiologic conditions [PDF]
Stress may contribute to the development and progression of gastrointestinal disorders. Activation of the hypothalamic–pituitary–adrenocortical (HPA) axis is one of the main characteristics of stress. For several decades it was generally accepted that glucocorticoids released during stress are ulcerogenic hormones. We designed some experimental studies
openaire +2 more sources
Nitrate protects the three major barriers of the gastric mucosa, alleviating bleeding and inflammation of ethanol‐induced gastric ulcer in rats, and promotes migration of gastric epithelial cells, accelerating the restoration of the ulcerated epithelium, which is strongly related to TFF2, a gastric mucosal protective factor negatively regulated by the ...
Ying Liu +10 more
wiley +1 more source
Protocol for the effective feedback to improve primary care prescribing safety (EFIPPS) study : a cluster randomised controlled trial using ePrescribing data [PDF]
High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions to improve care are attractive because they are relatively cheap to widely implement. There is good evidence that feedback has small to moderate effects,
Barnett, Karen; id_orcid +17 more
core +1 more source
Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats
Background/AimsThis study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-l-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats.Methods : Sprague-Dawley rats were ...
Yoon Jeong Choi +9 more
doaj +1 more source
A novel gastroprotective agent Osajin
A NOVEL GASTROPROTECTIVE AGENT ...
HAMZAOĞLU, ERGİN +5 more
openaire +4 more sources
Nitric oxide synthase induction and cytoprotection of rat gastric mucosa from injury by ethanol
The present study determined the effects of nitric oxide (NO) synthase induction on ethanol-mediated damage to rat gastric mucosa. NO synthase activity was determined by [14C]arginine conversion to radiolabeled citrulline.
B. L. Tepperman, B. D. Soper
core +1 more source

