Results 61 to 70 of about 285 (135)
AntioxidantsNonsteroidal anti-inflammatory drug-based therapies are the cause of 20–30% cases of gastric lesions in chronic users worldwide. Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of
Maribel Valenzuela-González +10 more
doaj +1 more source
Calcitonin Gene‐Related Peptide Signalling in Alcohol Use Disorders: A Scoping Review
Drug and Alcohol Review, Volume 45, Issue 4, May 2026.ABSTRACT Issue Alcohol use disorders (AUD) represent a major global health burden, and currently available pharmacological treatments show limited and heterogeneous efficacy. Calcitonin gene‐related peptide (CGRP) is a pleiotropic neuropeptide involved in stress regulation and neuroimmune signalling, and is an established therapeutic target in migraine.
Lanfranco Pellesi +2 more
wiley +1 more source
Recommendation for gastroprotection in gastrointestinal bleeding prevention
Srpski arhiv za celokupno lekarstvo, 2016 Incidence of gastrointestinal bleeding in most populations is about 1 per 1,000 inhabitants. More than 65% of all bleeding episodes are associated with drug use. The most often involved are non-steroidal antiinflammatory drugs and low doses of acetyl-salicylic acid. The mortality within the first month after the bleeding episode is about 10-
Nemanja Damjanov +5 more
openaire +4 more sources
Notulae Scientia BiologicaeIndomethacin, a widely used NSAID, induces gastric injury via prostaglandin depletion, oxidative stress, and immune imbalance. This study evaluated the gastroprotective effects of Argyreia acuta leaf ethanol extract (EEAAL) in a murine model of ...
Tran Thi Phuong NHUNG +2 more
doaj +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Choledochoduodenal fistula (CDF) is an abnormal communication between the common bile duct and the duodenum. While gallstones are the primary cause, peptic ulcer‐related CDF has become rare due to the widespread antiulcer therapy. Nevertheless, CDF remains clinically relevant as symptoms are often vague and diagnosis is frequently incidental ...
Yuki Miyashita +7 more
wiley +1 more source
Glucocorticoids are gastroprotective under physiologic conditions [PDF]
Therapeutic Advances in Chronic Disease, 2011 Stress may contribute to the development and progression of gastrointestinal disorders. Activation of the hypothalamic–pituitary–adrenocortical (HPA) axis is one of the main characteristics of stress. For several decades it was generally accepted that glucocorticoids released during stress are ulcerogenic hormones. We designed some experimental studies
openaire +2 more sources
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Health impacts of honey. ABSTRACT Honey is a natural and nutritious product of the honey bee (Apis mellifera) with low water content. Its color ranges from white to amber, with taste varying accordingly. The chemical form and viscosity of honey depend on its composition.
Ecem Bolat +7 more
wiley +1 more source
BiomedicinesPain is the most frequent symptom of disease. In treating pain, a lower incidence of adverse effects is found for paracetamol versus other non-steroidal anti-inflammatory drugs.
Josué Vidal Espinosa-Juárez +5 more
doaj +1 more source
Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats
Gut and Liver, 2016 Background/AimsThis study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-l-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats.Methods : Sprague-Dawley rats were ...
Yoon Jeong Choi +9 more
doaj +1 more source
A novel gastroprotective agent Osajin
, 2016 A NOVEL GASTROPROTECTIVE AGENT ...
HAMZAOĞLU, ERGİN +5 more
openaire +4 more sources