Results 41 to 50 of about 285 (135)

Gastroprotective, Antioxidant, Anti-Inflammatory, and Toxicological Evaluation of Stem Bark Extracts of Vitellaria paradoxa and Parkia biglobosa

Pharmaceuticals
Background/Objectives: Oxidative stress is a pathophysiological factor that causes challenging issues in the treatment of several diseases, including gastric ulcer, inflammatory diseases, and adenocarcinomas. V. paradoxa and P.
Brice Dangnon, Durand Dah-Nouvlessounon, S. M. Ismaël Hoteyi, Haziz Sina, Justinian Andrei Tomescu, Kouassi Jean-Michel Akpo, Maxime Machioud Sangare-Oumar, Adolphe Adjanohoun, Olubukola Oluranti Babalola, Emanuel Vamanu, Lamine Baba-Moussa   +10 more
doaj   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

Food Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman, Shefali Arora, Parteek Prasher, Sukanya Chhetri, Pankaj Bhandari, William N. Setzer, Javad Sharifi‐Rad   +6 more
wiley   +1 more source

Gastroprotective potential of Dolichandrone falcata extract via modulation of oxidative stress, inflammation, and mucosal healing

Journal of Applied Pharmaceutical Research
Background: Dolichandrone falcata, traditionally used for gastrointestinal disorders, has demonstrated antiulcer activity, but the underlying protective mechanisms remain unclear. This study evaluated the methanolic extract of D.
Sagar Kamble, Ajay Salvi, Shivaji Patil, Shashikant Modekar, Sachin Kothawade   +4 more
doaj   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Traditional medicine and gastroprotective crude drugs

Journal of Ethnopharmacology, 2005
A frequent question when dealing with the search for gastroprotective compounds from natural sources is how far or close are both the plant preparations and extract amounts from the doses recommended in traditional medicine and what should be considered realistic levels for experimental studies. The administration way is oral and therefore extracts and
Schmeda-Hirschmann, G., Yesilada, E.
openaire   +6 more sources

Rebamipide as an Adjunctive Therapy for Gastrointestinal Diseases: An Umbrella Review

Pharmaceuticals
Objective: This umbrella review aimed to synthesize evidence from meta-analyses on the efficacy of rebamipide in major gastrointestinal disorders and dyspeptic symptoms.
Igor V. Maev, Alsu R. Khurmatullina, Dmitrii N. Andreev, Andrew V. Zaborovsky, Yury A. Kucheryavyy, Philipp S. Sokolov, Petr A. Beliy   +6 more
doaj   +1 more source

Proton Pump Inhibitors Prescribing Behaviors and Rationalization Strategies Among Healthcare Providers in Southeast Asia

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Long‐term proton pump inhibitor (PPI) therapy raises significant concerns regarding cost‐effectiveness and adverse effects, necessitating effective deprescribing strategies. An evaluation of 763 Southeast Asian healthcare providers revealed two distinct prescriber phenotypes, where a proactive cluster utilized diverse, guideline‐based rationalization ...
Duc Trong Quach, Tien Manh Huynh, Augusto Jose G. Galang, Hang Viet Dao, Sakkarin Chirapongsathorn, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Andrew Ming‐Liang Ong, Wee Kooi Cheah, Kalwinder Singh Khaira, So Fie Tan, Jose Sollano, Ari Fahrial Syam, Tju Siang Chua, Somchai Leelakusolvong, Yeong Yeh Lee   +15 more
wiley   +1 more source

Gastroprotective Strategy in Aspirin Users

Journal of the Chinese Medical Association, 2009
343 Aspirin, acetylsalicylic acid, was synthesized by Hoffman of Bayer Laboratories in 1897. Aspirin irreversibly inhibits platelet cyclooxygenase (COX-1) activity, thus preventing the synthesis of thromboxaneA2, and thereby inhibiting platelet aggregation and thrombi formation.
openaire   +2 more sources

RETRACTED: Ahmed et al. Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats. Pharmaceutics 2020, 12, 140

Pharmaceutics
The journal retracts the article, “Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats” [...]
Osama A. A. Ahmed, Usama A. Fahmy, Rana Bakhaidar, Mohamed A. El-Moselhy, Solomon Z. Okbazghi, Al-Shaimaa F. Ahmed, Asmaa S. A. Hammad, Nabil A. Alhakamy   +7 more
doaj   +1 more source

The gastroprotective role of yellow kepok Banana (Musa x Paradisiaca L. Var. Kepok) peel extract and influence on markers of oxidative stress: Malondialdehyde and nitric oxide [PDF]

Scripta Medica, 2023
Background/Aim: Flavonoids, tannins, saponins and polyphenols in yellow kepok banana (Musa x paradisiaca L. var. kepok) peel potentially could be a solution for peptic ulcer prevention.
Samiasih Amin, Khoiriyah Khoiriyah, Norma Ethica Stalis, Rahmawati Sulistyaningtyas Ayu, Pranata Satriya, Rino Vanchapo Antonius   +5 more
doaj