Results 31 to 40 of about 285 (135)
Glucagon-like peptide-2 protects the gastric mucosa via regulating blood flow and metabolites
Frontiers in Endocrinology, 2022 IntroductionRefractory peptic ulcers lead to perforation and hemorrhage, which are fatal. However, these remain a therapeutic challenge. Gastric mucosal blood flow is crucial in maintaining gastric mucosal health. It’s reported that Glucagon-like peptide-
Jing Zhang +8 more
doaj +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray +6 more
wiley +1 more source
Pharmaceuticals, 2018 The development of the gastric lesion is complex and the result of the imbalance between aggressive and protective factors, involving the generation of free radicals and disturbance in nitric oxide (NO) production.
José Gerardo Carneiro +9 more
doaj +1 more source
International Journal of Nanomedicine, 2020 Mohammed M Mehanna,1,2 Amina Tarek Mneimneh,2 Souraya Domiati,3 Ahmed N Allam4 1Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; 2Department of Pharmaceutical Technology, Faculty of Pharmacy, Beirut Arab ...
Mehanna MM +3 more
doaj
Arthritis &Rheumatology, Volume 78, Issue 8, Page 1731-1740, August 2026.Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig +5 more
wiley +1 more source
The gastroprotective properties of
Modern Rheumatology Journal, 2011 The gastroprotective properties of tizanidine, a centrally acting myorelaxant, are discussed. It is noted that there is no strong evidence suggesting the ability of tizanidine to reduce the risk of serious gastrointestinal complications arising from with the use of nonsteroidal anti-inflammatory drugs and to decrease their need (average daily dose). It
openaire +4 more sources
Possibilities of gastroprotective therapy in NSA1Dinduced gastropathies with De-Nol
Научно-практическая ревматология, 2004 Objective. To assess efficacy of De-Nol in NSAID-induced gastropathies. Material and Methods. 45 pts with rheumatic diseases taking NSAID with gastric and/or duodenal ulcer up to 1 cm of size or multiple (>10) gastric erosions (MGE) confirmed with ...
A. E. Karateev +2 more
doaj +1 more source
Pharmaceuticals, 2023 We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric +24 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 8, August 2026.Dietary enrichment of Helix aspersa mucus with Urtica dioica or Ceratonia siliqua extracts increased its phenolic, flavonoid, protein, and glycoprotein content in a dose‐dependent manner, with nettle showing the strongest effect. In an ethanol‐induced rat model of gastric ulcer, the 30% nettle‐enriched mucus (SSUD30%) markedly reduced gastric lesions ...
Khaoula Gharbi +6 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 499-506, August 2026.In patients with atherothrombotic disease on antithrombotic therapy, P‐CABs demonstrated a significantly superior protective effect against clinically significant upper GI haemorrhage compared to PPIs (aHR 0.22; p = 0.016). This real‐world study highlights P‐CABs as a more potent gastroprotective strategy for high‐risk populations requiring intensive ...
Min Joo Yoon +6 more
wiley +1 more source