Results 11 to 20 of about 2,582 (208)

Gastroprotection of Calein D against Ethanol-Induced Gastric Lesions in Mice: Role of Prostaglandins, Nitric Oxide and Sulfhydryls

Molecules, 2019
Peptic ulcers are currently treated with various drugs, all having serious side effects. The aim of this study was to evaluate the gastroprotective activity of calein D (from Calea urticifolia), a sesquiterpene lactone with a germacrane skeleton. Gastric
Jesús Arrieta, Yaraset López-Lorenzo
exaly   +4 more sources

Dual antithrombotic therapy and gastroprotection in atrial fibrillation: an observational primary care study [PDF]

BJGP Open, 2022
Background: Patients with both atrial fibrillation (AF) and cardiovascular disease (CVD) may receive dual antithrombotic therapy (DAT) with both an anticoagulant and ≥1 antiplatelet agents.
Charis Xuan Xie, John Robson, Crystal Williams, Chris Carvalho, Stuart Rison, Zahra Raisi-Estabragh   +5 more
doaj   +2 more sources

Comparative Efficacy of Rebamipide, Pantoprazole, and Their Combination for Gastroprotection in Patients with Atrial Fibrillation Receiving Direct Oral Anticoagulants: The Randomized REGATA Study [PDF]

Medical Sciences
Background: Patients with atrial fibrillation (AF) receiving direct oral anticoagulants (DOAC) are at an elevated risk of gastrointestinal (GI) mucosal damage and bleeding.
Natalya M. Vorobyeva, Irina P. Malaya, Vadim D. Zakiev, Antonina A. Masharova, Tatiana P. Pinchuk, Irina V. Kostomarova, Valentina S. Ostapenko, Yulia V. Kotovskaya, Olga N. Tkacheva   +8 more
doaj   +2 more sources

RETRACTED: Ahmed et al. Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats. Pharmaceutics 2020, 12, 140

Pharmaceutics
The journal retracts the article, “Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats” [...]
Osama A. A. Ahmed, Usama A. Fahmy, Rana Bakhaidar, Mohamed A. El-Moselhy, Solomon Z. Okbazghi, Al-Shaimaa F. Ahmed, Asmaa S. A. Hammad, Nabil A. Alhakamy   +7 more
doaj   +2 more sources

P-CAB vs. PPI for Upper Gastrointestinal Bleeding Prevention in Patients With Atherothrombotic Disease on Antithrombotic Therapy: A CDM Cohort Study. [PDF]

Aliment Pharmacol Ther
In patients with atherothrombotic disease on antithrombotic therapy, P‐CABs demonstrated a significantly superior protective effect against clinically significant upper GI haemorrhage compared to PPIs (aHR 0.22; p = 0.016). This real‐world study highlights P‐CABs as a more potent gastroprotective strategy for high‐risk populations requiring intensive ...
Yoon MJ, Lee S, Jung HK, Kim MH, Yu S, Jeong ES, Tae CH.   +6 more
europepmc   +2 more sources

Low‐Dose Aspirin Induced Gastric Ulcer in a Patient With TIA: A Clinical Caution for Aspirin Therapy Without Gastroprotection [PDF]

Clinical Case Reports
Balancing the cerebrovascular benefits of low‐dose aspirin (LDA) with its significant gastrointestinal (GI) bleeding risk is a critical challenge in secondary stroke prevention.
Kainat Husain, Muhammad Ibrahim, Fazeela Bibi, Khalil El Abdi, Bilal Aslam, Abdullah Saud, Vohra Maham Hassan, Aminullah Betanai, Muhammad Muneeb, Said Hamid Sadat   +9 more
doaj   +2 more sources

RETRACTED: Alhakamy et al. Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats. Biomolecules 2020, 10, 1006

Biomolecules
The journal retracts the article, “Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats” [...]
Nabil A. Alhakamy, Shaimaa M. Badr-Eldin, Osama A. A. Ahmed, Abdulrahman A. Halwani, Hibah M. Aldawsari, Mohamed A. El-Moselhy, Aliaa Anter, Sara S. Sharkawi, Muhammad H. Sultan, Osama A. A. Madkhali, Muhammed A. Bakhrebah, Mohammad N. Alomary, Wesam H. Abdulaal, Usama A. Fahmy   +13 more
doaj   +2 more sources

Percutaneous Closure of Patent Foramen Ovale in a Patient With Incomplete Cor Triatriatum Sinister: A Case Report. [PDF]

J Clin Ultrasound
We present the case of a 55‐year‐old male who experienced a cryptogenic ischemic stroke, likely due to a patent foramen ovale (PFO) in the setting of an incomplete cor triatriatum sinister (CTS) and a 30 mm GORE Cardioform Septal Occluder was successfully implanted.
Apostolos A, Drakopoulou M, Tolis E, Trantalis G, Kachrimanidis I, Vlachakis P, Tsioufis K, Toutouzas K, Aggeli K.   +8 more
europepmc   +2 more sources

Proton pump inhibitor co-therapy in patients receiving non-vitamin K antagonist oral anticoagulants: current evidence, gastrointestinal bleeding prevention, and clinical considerations [PDF]

Frontiers in Cardiovascular Medicine
BackgroundNon-vitamin K antagonist oral anticoagulants (NOACs) are widely prescribed for stroke prevention in atrial fibrillation (AF). Although they reduce intracranial hemorrhage compared with warfarin, gastrointestinal bleeding (GIB), particularly ...
Dong-Hyeok Kim, Yeji Kim, Moon-Hyun Kim, Jeongmin Kang, Junbeom Park   +4 more
doaj   +2 more sources

Use of STOPPFrail Medications Following Receipt of the Danish Terminal Grant: A Nationwide Descriptive Study. [PDF]

Basic Clin Pharmacol Toxicol
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
Henriksen DP, Øhlenschlæger T, Dunvald AD.   +2 more
europepmc   +2 more sources