Results 1 to 10 of about 235 (87)

Gastroprotection of Calein D against Ethanol-Induced Gastric Lesions in Mice: Role of Prostaglandins, Nitric Oxide and Sulfhydryls

Molecules, 2019
Peptic ulcers are currently treated with various drugs, all having serious side effects. The aim of this study was to evaluate the gastroprotective activity of calein D (from Calea urticifolia), a sesquiterpene lactone with a germacrane skeleton. Gastric
Audifás-Salvador Matus-Meza, Jesus Arrieta, Yaraset López-Lorenzo   +2 more
exaly   +3 more sources

Are the clinical guideline recommendations on gastroprotection being followed? A review in patients taking nonsteroidal anti-inflammatory drugs

Revista De Gastroenterología De México (English Edition), 2016
Introduction and aims: The chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) can cause complications in the gastrointestinal tract. The use of proton pump inhibitors (PPIs) is recommended in high-risk patients to prevent them.
L Uscanga
exaly   +3 more sources

Dual antithrombotic therapy and gastroprotection in atrial fibrillation: an observational primary care study

BJGP Open, 2022
Background: Patients with both atrial fibrillation (AF) and cardiovascular disease (CVD) may receive dual antithrombotic therapy (DAT) with both an anticoagulant and ≥1 antiplatelet agents.
Charis Xuan Xie, John Robson, Crystal Williams, Chris Carvalho, Stuart Rison, Zahra Raisi-Estabragh   +5 more
doaj   +1 more source

Freshwater Clam Extract Attenuates Indomethacin-Induced Gastric Damage In Vitro and In Vivo

Foods, 2022
Contemporary pharmacological studies have reported that freshwater clam (Corbicula fluminea) can provide a broad spectrum of bioactivities, including antioxidant, anticancer, antihypertensive, hepatoprotective, and hypocholesterolemic effects. The aim of
Fuad Sauqi Isnain, Nai-Chen Liao, Hui-Yun Tsai, Yu-Jie Zhao, Chien-Hua Huang, Jue-Liang Hsu, Agustin Krisna Wardani, Yu-Kuo Chen   +7 more
doaj   +1 more source

Gastroprotective effect of hydroalcoholic extract of Ocimum africanum leaves [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
Ocimum africanum Lour. (hairy basil, hoary basil or lemon basil) is an aromatic herb in Asian and Thai cuisine that has been used as a carminative, a digestion enhancement and remedy for gastrointestinal disturbance in Thai traditional medicine.
Jaruwat Bunwijit, Bungorn Sripanidkulchai, Wanassanun Pannangrong, Jintana Junlatat, Kittisak Sripanidkulchai   +4 more
doaj   +1 more source

Gastric Ulcer Healing Property of Bryophyllum pinnatum Leaf Extract in Chronic Model In Vivo and Gastroprotective Activity of Its Major Flavonoid

Frontiers in Pharmacology, 2021
Gastric ulcer is a common disease that develops complications such as hemorrhages and perforations when not properly treated. Extended use of drugs in the treatment of this pathology can provoke many adverse effects.
Edilane Rodrigues Dantas De Araújo, Gerlane Coelho Bernardo Guerra, Anderson Wilbur Lopes Andrade, Júlia Morais Fernandes, Valéria Costa Da Silva, Emanuella De Aragão Tavares, Aurigena Antunes De Araújo, Raimundo Fernandes de Araújo Júnior, Raimundo Fernandes de Araújo Júnior, Raimundo Fernandes de Araújo Júnior, Raimundo Fernandes de Araújo Júnior, Silvana Maria Zucolotto, Silvana Maria Zucolotto, Silvana Maria Zucolotto   +13 more
doaj   +1 more source

Gastroprotective Effects of Oral Glycosaminoglycans with Sodium Alginate in an Indomethacin-Induced Gastric Injury Model in Rats

Veterinary Sciences, 2023
The gastrointestinal (GI) mucosal barrier is often exposed to inflammatory and erosive insults, resulting in gastric lesions. Glycosaminoglycans (GAGs), such as hyaluronic acid (HA), chondroitin sulfate (CS), and N-acetylglucosamine (NAG) have shown ...
Sara Traserra, Héctor Cuerda, Adriana Vallejo, Sergi Segarra, Roger Sabata, Marcel Jimenez   +5 more
doaj   +1 more source

Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice

BMC Musculoskeletal Disorders, 2006
Background Gastrointestinal harm, known to occur with NSAIDs, is thought to be lower with NSAID and gastroprotective agent, and with inhibitors selective to cyclooxygenase-2 (coxibs) at usual plasma concentrations.
Phillips Ceri J, Derry Sheena, Moore R Andrew, McQuay Henry J   +3 more
doaj   +1 more source

First Evidence of Gastroprotection by Schinus molle: Roles of Nitric Oxide, Prostaglandins, and Sulfhydryls Groups in Its Mechanism of Action

Molecules, 2022
Schinus molle is a plant traditionally used in Mexico to treat gastric disorders. However, no scientific evidence has been reported on its gastroprotective effect. The aim of the current contribution was to conduct a bioassay-guided study on S.
María Elena Sánchez-Mendoza, Yaraset López-Lorenzo, Leticia Cruz-Antonio, Daniel Arrieta-Baez, Miranda Carolina Pérez-González, Jesús Arrieta   +5 more
doaj   +1 more source

The gastroprotective effect of ethyl acetate fraction of hot water extract of Trichosanthes cucumerina Linn and its underlying mechanisms

BMC Complementary and Alternative Medicine, 2017
Background Antacids, anticholinergic drugs, histamine H2- receptor antagonists and irreversible proton pump inhibitors have been used for the treatment of gastric ulcers. However, prolonged use of these drugs may lead to series of adverse effects such as
Ramani Karunakaran, M. Ira Thabrew, G. Mayuri Thammitiyagodage, B. Prasanna Galhena, L.D.A. Menuka Arawwawala   +4 more
doaj   +1 more source