Results 91 to 100 of about 2,310 (209)

GASTROPROTECTIVE ACTIVITY OF TEPHROSIA PURPUREA

International journal of Research in Ayurveda & Pharmacy, 2013
The antiulcer activity of methanolic extract of Tephrosia purpurea (Fabaceae) aerial parts was investigated in pylorus ligation and ethanol induced ulcer model in wistar rats. Toxicity study sho wed 250 mg/kg as the therapeutic dose and produced significant inhibition of the gastric lesions induced by pylorus ligation and ethanol induced gastric ulcers.
A Tamil Selvan, Rizwan Shaik, R Suthakaran, G Mohan Kumar   +3 more
openaire   +1 more source

Gastroprotective potential of frutalin, a d-galactose binding lectin, against ethanol-induced gastric lesions

, 2012
The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2ml of ethanol (
Noronha Coelho de Souza, Lílian, Moreira Guedes, Marjorie, Prado Vasconcelos, Renata, de Oliveira Monteiro-Moreira, Ana Cristina, de Vasconcellos Abdon, Ana Paula, Araújo Castro, Carolina, de Azevedo Moreira, Renato, Coelho de Souza, Greicy, Rolim Campos, Adriana, Pereira Lima Júnior, Roberto César   +9 more
core   +1 more source

Morphologic and Pharmacological Investigations in the Epicatechin Gastroprotective Effect [PDF]

, 2012
Previous studies of the gastroprotective activity of plants have highlighted the importance of the polyphenolic compound epicatechin (EC) in the treatment of gastric ulcers.
Hiruma-Lima, Clélia Akiko, Rozza, A. L., Pellizzon, C. H., Tanimoto, A.   +3 more
core   +1 more source

Selenium Nanoparticles-Embedded Chitosan Microspheres and Their Effects Upon Alcohol-Induced Gastric Mucosal Injury in Rats: Rapid Preparation, Oral Delivery, and Gastroprotective Potential of Selenium Nanoparticles

International Journal of Nanomedicine, 2020
Kaikai Bai,1,2,* Bihong Hong,1,2,* Ran Tan,1,2 Jianlin He,1,2 Zhuan Hong1,2 1Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, Republic of China; 2Technical Innovation Center for Utilization of Marine Biological Resources ...
Bai K, Hong B, Tan R, He J, Hong Z
doaj  

In vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions

Pharmaceutical Biology, 2018
Context: Okra, Abelmoschus esculentus (L.) (Malvaceae), is a medicinal plant widely used in Turkish traditional medicine for the treatment of various diseases such as ulcers and gastritis.
Deniz Ortaç, Mustafa Cemek, Turan Karaca, Mehmet E. Büyükokuroğlu, Zafer Ö. Özdemir, Ayşe Tuba Kocaman, Sadık Göneş   +6 more
doaj   +1 more source

Gastroprotective effect of Byrsonima sericea DC leaf extract against ethanol-induced gastric injury and its possible mechanisms of action

Anais da Academia Brasileira de Ciências, 2012
Byrsonima sericea leaves are extensively used in folk medicine in Brazil against gastric disorders. This study investigated the chemical constituents of B.
Patrícia A. Rodrigues, Selene M. Morais, Carolina M. Souza, Davi V. Magalhães, Ícaro G.P. Vieira, Geanne M. Andrade, Vietla S. Rao, Flávia A. Santos   +7 more
doaj   +1 more source

A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling

, 2018
The advent of angiotensin II type 1 receptor blockers (ARBs) as intriguing gastroprotective candidates and the superior pharmacokinetics and pharmacodynamics displayed by irbesartan compared to many other ARBs raised the interest to investigate its ...
Nancy N. Shahin, Marwa M. Safar, Noha F. Abdelkader   +2 more
core   +2 more sources

Mitochondria-targeted hydrogen sulfide donors versus acute oxidative gastric mucosal injury

, 2022
Hydrogen sulfide (H2S) as a gaseous molecule prevents gastrointestinal (GI)-tract against various injuries. This study aimed to evaluate for the first time the detailed molecular mechanism of mitochondria-targeting H2S-prodrugs, AP39 and RT01 in ...
Magierowski, Marcin, Torregrossa, Roberta, Korbut, Edyta, Magierowska, Katarzyna, Śliwowski, Zbigniew, Szetela, Małgorzata, Wójcik-Grzybek, Dagmara, Bakalarz, Dominik, Whiteman, Matthew, Cieszkowski, Jakub   +9 more
core   +1 more source

NOVEL PROTECTIVE ROLE OF MONTELUKAST AGAINST ASPIRIN INDUCED GASTRIC ULCERATION IN RABBITS - MONTELUKAST; A REVOLUTIONARY ASPECT

Pakistan Armed Forces Medical Journal, 2020
Objective: To assess the gastroprotective effect of montelukast on aspirin induced gastric mucosal ulceration in rabbits. Study Design: Laboratory based quasi experimental study.
Syeda Urooj Zaidi, Muhammad Waqar Aslam Khan, Sumetha Yaseen, Mahwish Gul, Zubaida Rashid, Maryam Saqib   +5 more
doaj  

Features of Clinical Course of Chronic Gastroduodenitis, Morphological Changes and Gastroprotection State in Children with Zinc Deficiency

, 2014
Introduction. One of the urgent problems of modern pediatrics are diseases of the digestive tract. Over the past years there was proved negative role of zinc deficiency in the formation of digestive diseases.
Yu.V. Marushko, S.G. Gichka, A.O. Asonov
core   +1 more source