Results 31 to 40 of about 14,999 (134)
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
GATA3-ext cell sensitivity is due to on-target inhibition of G9A/GLP.
, 2016 (A-G) Dose response curves (DRC) and colony formation assay (CFA) in reduced supplement-containing medium. MCF10A control and cells expressing GATA3-ext were treated with the indicated concentrations of HMT inhibitors (A-F) or structurally related ...
Barbara Mair (3097941) +8 more
core +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
, 2017 Supplemental Materials show that KMT1A was highly expressed in BCSCs compared with either BCNSCs or normal bladder tissue, and positively regulated the self-renewal and tumorigenicity of human BCSCs via KMT1A-GATA3-STAT3 circuit.
Zhao Yang (358244) +7 more
core +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
MedComm, Volume 7, Issue 4, April 2026.Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
Proposed model of PYCARD-AS1-mediated PYCARD regulation.
, 2019 PYCARD transcription is activated in the case of PYCARD-AS1 silencing (A). Upon transcribed from the opposite strand of the PYCARD gene, a fraction of PYCARD-AS1 transcripts localize at PYCARD promoter via the 5′ region, and interact with DNMT1 and G9a ...
Chunfang Gao (468281) +10 more
core +1 more source