Results 21 to 30 of about 14,999 (134)

Gene of the month: GATA3 [PDF]

, 2023
GATA binding protein 3 (GATA3) is a zinc-finger pioneer transcription factor involved in diverse processes. GATA3 regulates gene expression through binding nucleosomal DNA and facilitating chromatin remodelling.
Lloyd, K., Cumberbatch, M., Jubber, I., Griffin, J., Qiang, Z.   +4 more
core   +1 more source

Multi-Omics Analysis of Human Blood Cells Reveals Unique Features of Age-Associated Type 2 CD8 Memory T Cells. [PDF]

Aging Cell
Aging drives the accumulation of CXCR3‐ central memory CD8 T cells that exhibit Th2‐like transcriptional and epigenetic programs. These cells display a pathogenic Th2‐skewed profile and are associated with age‐related diseases, including asthma, chronic liver disease, and type 2 diabetes.
Matsui H, Cervantes M, Khalid MM, Tomusiak A, Dwaraka V, Landgrave-Gomez J, Kumaar PVA, Chen Q, Lasky-Su J, Stone J, Tiwari R, Kwok R, Ichikawa S, Ambrose BD, Riley RR, Hormazabal GV, Adkisson-Floro A, Alexandru AC, Smith R, Schilling B, Kasler HG, Verdin E.   +21 more
europepmc   +2 more sources

Screen and identification of BVES-AS1-201-50aa.

, 2023
(A) Venn diagram showed the lncRNAs that are aberrant expression in CRC, are associated with poor prognosis of CRC patients, and are predicted to have encoding potential.
Weiwei Zheng (140828), Yucheng Song (14231285), Yingchang Guo (16425979), Guangtan Zhang (16425982), Xuebin Bao (16425988), Junwei Bai (9730322), Xiaofei Song (3111648), Qinhui Zhu (16425985), Chao Zhang (51048), Gang Wu (23885)   +9 more
core   +1 more source

The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.

, 2023
The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.
Weiwei Zheng (140828), Yucheng Song (14231285), Yingchang Guo (16425979), Guangtan Zhang (16425982), Xuebin Bao (16425988), Junwei Bai (9730322), Xiaofei Song (3111648), Qinhui Zhu (16425985), Chao Zhang (51048), Gang Wu (23885)   +9 more
core   +1 more source

MicroRNA-886 suppresses osteosarcoma cell proliferation and its maturation is suppressed by long non-coding RNA OXCT1-AS1

, 2022
This study aimed to investigate the roles of microRNA-886 (miR-886) and long non-coding RNA (lncRNA) OXCT1-AS1 in osteosarcoma (OS). We predicted that they might interact with each other.
Han Liu (288039), Wen Dai (1607932)
core   +1 more source

Table_1_Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells.DOCX

, 2018
Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.
Nathaniel Chapman (5903219), Laura C. Kim (5903216), Thomas M. Aune (237367), Charles F. Spurlock (5903222), Guzel Shaginurova (5903213), Hunter R. Gibbons (5903210)   +5 more
core   +1 more source

GATA3 : a promising marker for metastatic breast carcinoma in serous effusion specimens [PDF]

, 2014
Background\ud \ud The utility of GATA3 as a marker for metastatic breast carcinoma in serous effusion specimens was investigated. \ud \ud Methods\ud \ud Cell block sections from 74 serous effusion specimens (32 ascitic, 2 pericardial and 40 pleural ...
Paul W. Shield, Shield, Paul W., David J. Papadimos, Walsh, Michael D., Michael D. Walsh, Papadimos, David J.   +5 more
core   +1 more source

DataSheet_2_Long Non-Coding RNA CD27-AS1-208 Facilitates Melanoma Progression by Activating STAT3 Pathway.zip

, 2022
Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704), Jingjing Ma (419752), Tianwen Gao (262800), Peng Xu (17962), Qiong Shi (244677), Xiuli Yi (166944), Yuqi Yang (1608304), Weinan Guo (4727631), Sen Guo (1846828), Lin Liu (74495), Chunying Li (166955), Weigang Zhang (1333242), Yu Liu (6938), Qiao Yue (11939732)   +13 more
core   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source