Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells [PDF]
Frontiers in Immunology, 2018 Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.
Laura C Kim +2 more
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Long Noncoding RNA GATA3-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Suppression of PTEN, CDKN1A, and TP53 [PDF]
Canadian Journal of Gastroenterology and Hepatology, 2019 Background. Long noncoding RNAs (lncRNAs) have been known to play important roles in the progression of various types of human cancer. LncRNA GATA3 antisense RNA 1, GATA3-AS1, has been reported to be associated with T-cell development and differentiation.
Hongying Tang, Le Wang, Ning Zhou
exaly +7 more sources
Dysregulation of lncRNA GATA3-AS1 Is Involved in the Pathogenesis of Pulpitis by the Regulation of miR-17-3p [PDF]
Journal of Inflammation ResearchLeilei Li,1,* Yumei Wang,2,* Mingyan Hu1 1Department of Stomatology, Dongying People’s Hospital, Dongying, Shandong, People’s Republic of China; 2Department of Stomatology, Dongying District People’s Hospital, Dongying, Shandong, People’s ...
Li L, Wang Y, Hu M
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LncRNA GATA3‑AS1‑miR‑30b‑5p‑Tex10 Axis Modulates Tumorigenesis in Pancreatic Cancer [PDF]
Oncology Reports, 2021 Long noncoding RNAs (lncRNAs) have been widely recognized to play an important role in a variety of diseases. Abnormal regulation of lncRNA GATA3‑antisense RNA 1 (AS1) occurs in several cancers, but whether it is involved in the progression of pancreatic cancer (PC) remains unknown. The present study aimed to investigate the biological effects of GATA3‑
Liu Y, Xu G, Li L.
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LncRNA GATA3-AS1 Facilitates Tumour Progression and Immune Escape in Triple-Negative Breast Cancer Through Destabilization of GATA3 but Stabilization of PD-L1 [PDF]
Cell Proliferation, 2020 Abstract Objectives Long non‐coding RNAs (lncRNAs) have been demonstrated as crucial regulators in cancer, but whether they are involved in the immune response of cancer cells remains largely undiscovered.
Zhigao Li, Yingqiang Fu
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LncRNA GATA3-AS1 promotes the proliferation and migration of breast cancer cells and the mechanisms underlying its action [PDF]
Yixue xinzhi zazhi, 2022 Objective Long non-coding RNA (LncRNA) is closely related to the occurrence and development of various tumors. This study aimed to investigate the biological role and mechanism of LncRNA GATA3-AS1 in breast cancer progression.Methods The expression level
Qi JIANG, Yi-Qing XI, Lei WEI
doaj +2 more sources
Frontiers in Oncology, 2021 Breast cancer is the most common neoplasm among females. Estrogen receptor (ESR) signaling has a prominent impact in the pathogenesis of breast cancer. Among the transcription factors associated with ESR signaling, FOXM1, GATA3, FOXA1 and ESR1 have been ...
Yazdan Asgari +2 more
exaly +3 more sources
Maternal Blood as a Window to the Fetal Heart: Novel Biomarkers for Early Detection of Septal Defects [PDF]
BiomedicinesCongenital heart defects (CHDs) represent the most common category of congenital malformations and constitute a significant cause of infant morbidity and mortality.
Alexandru Carauleanu +12 more
doaj +2 more sources
Differential lncRNA/mRNA expression profiling and ceRNA network analyses in amniotic fluid from foetuses with ventricular septal defects [PDF]
PeerJ, 2023 Background Long noncoding RNAs (lncRNAs) have been shown to be involved in the regulation of numerous biological processes in embryonic development. We aimed to explore lncRNA expression profiles in ventricular septal defects (VSDs) and reveal their ...
Huaming Wang +5 more
doaj +2 more sources
Frontiers in Genetics, 2023 Background: Maternal body fluids contain abundant cell-free fetal RNAs which have the potential to serve as indicators of fetal development and pathophysiological conditions.
Huaming Wang +5 more
doaj +1 more source