Results 101 to 110 of about 4,830,735 (205)

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Pulmonary Adenocarcinoma Metastasising to Mandibular Gingiva: Diagnostic Insights

Oral Surgery, EarlyView.
ABSTRACT Background Oral metastases from lung cancer are exceedingly rare and often mimic primary oral lesions, posing significant diagnostic challenges. Case Presentation We report a patient under oncological care for pulmonary adenocarcinoma who developed a rapidly enlarging 3‐cm mandibular gingival mass.
Caroline Alfaia‐Silva, Lisiane Cândido, Matheus A. S. Costa, Daniella S. C. Vieira, Filipe Modolo, Ricardo L. C. Albuquerque‐Júnior, Rogério O. Gondak   +6 more
wiley   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Treatment‐Associated Type 2/22 Helper T‐Cell States in Dupilumab‐Treated Atopic Dermatitis

Clinical &Experimental Allergy, EarlyView.
Mai Nishimura, Chiaki Nakamura‐Sakashita, Yasutomo Imai, Ayaka Ichikawa, Yoshiaki Matsushima, Keiichi Yamanaka   +5 more
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells.

, 2013
International audienceGroup 2 innate lymphoid cells (ILC2s; also called nuocytes, innate helper cells, or natural helper cells) provide protective immunity during helminth infection and play an important role in influenza-induced and allergic airway ...
Klein Wolterink, Roel, Vosshenrich, CAJ, Hendriks, Rudi, De Jong - de Bruijn, Marjolein, Pereira, DF, Di Santo, James P, di Santo, JP, Serafini, N, van Nimwegen, Menno, Vosshenrich, Christian A. J., Serafini, Nicolas, Veiga Fernandes, Henrique, Hendriks, Rudi W, de Bruijn, Marjolein J W, Klein Wolterink, Roel G J, Fernandes, HV, Fonseca Pereira, Diogo   +16 more
core   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Sex‐Modulated TACSTD2 Methylation and Hormone‐Receptor Axis Interactions in Glioblastoma: Insights Toward Mechanistic Understanding

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley   +1 more source

Metastasis of mucinous breast carcinoma to the lower alveolus as initial presentation: a diagnostic dilemma

Autopsy and Case Reports, 2022
Metastases in the oral cavity are rare and comprise approximately 1% of all oral malignancies. They usually involve the jaws but may also be found in the soft tissues and salivary glands.
Priyadarshini Guha, Zachariah Chowdhury
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