Results 1 to 10 of about 6,168 (196)
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells [PDF]
Frontiers in Immunology, 2018 Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.
Laura C Kim +2 more
exaly +5 more sources
The Multi-Faceted Role of Gata3 in Developmental Haematopoiesis [PDF]
Open Biology, 2018 The transcription factor Gata3 is crucial for the development of several tissues and cell lineages both during development as well as postnatally. This importance is apparent from the early embryonic lethality following germline Gata3 deletion, with ...
Katrin Ottersbach, Nada M Zaidan
exaly +5 more sources
Diagnostic and Prognostic Roles of GATA3 Immunohistochemistry in Urothelial Carcinoma
Medicina (Lithuania), 2023 This study aimed to evaluate the diagnostic and prognostic roles of GATA-binding protein 3 (GATA3) immunohistochemistry in urothelial carcinoma (UC) using a meta-analysis.
Nae-Yu Kim +2 more
exaly +4 more sources
Gene of the month: GATA3 [PDF]
Journal of Clinical Pathology, 2023 GATA binding protein 3 (GATA3) is a zinc-finger pioneer transcription factor involved in diverse processes. GATA3 regulates gene expression through binding nucleosomal DNA and facilitating chromatin remodelling. Post-translational modifications modulate its activity.
Qiang, Z. +4 more
openaire +4 more sources
Frontiers in Immunology, 2022 T helper-2 (Th2) cells and type 2 innate lymphoid cells (ILC2s) play crucial roles during type 2 immune responses; the transcription factor GATA3 is essential for the differentiation and functions of these cell types.
Rama K. Gurram +11 more
doaj +3 more sources
Mutation of GATA3 in Human Breast Tumors [PDF]
Oncogene, 2004 GATA3 is an essential transcription factor that was first identified as a regulator of immune cell function. In recent microarray analyses of human breast tumors, both normal breast luminal epithelium and estrogen receptor (ESR1)-positive tumors showed high expression of GATA3.
Charles M. Perou +2 more
exaly +3 more sources
GATA3 expression in the solid cell nest of thyroid
Indian Journal of Pathology and Microbiology, 2020 Solid cell nest (SCN) of thyroid is a benign histomorphological mimicker of papillary microcarcinoma. Previous studies have elucidated a few immunohistochemical markers of SCN that aid in its distinction from papillary microcarcinoma.
Pavithra Ayyanar +2 more
doaj +3 more sources
Endosalpingiosis Is Negative for GATA3 [PDF]
Archives of Pathology & Laboratory Medicine, 2021 Context.— Endosalpingiosis is a benign Müllerian inclusion that can mimic metastatic low-grade mammary carcinoma, particularly when encountered in axillary lymph nodes excised for breast cancer staging. Immunohistochemistry can be useful in histologically ambiguous cases, and a targeted immunopanel should ...
Marissa J, White +3 more
openaire +2 more sources
Whole-Exome Sequencing Reveals Pediatric Rare Syndromic Hearing Loss
罕见病研究, 2022 Objective To discuss the significance of genetic diagnosis of children with syndromic hearing loss by using whole-exome sequencing. Methods The clinical data of 34 children with sensorineural hearing loss were collected and the whole exons of genome of ...
QU Chunyan +5 more
doaj +1 more source
International Journal of Health Services Research and Policy, 2021 The purpose of our study is to examine immunohistochemically the correlation of GATA binding protein 3 (GATA3), E-cadherin, p53 and Ki-67 expression with histological type/molecular subtype and clinicopathological parameters in breast cancer. Methods and
Yeliz ARMAN KARAKAYA
doaj +1 more source