Results 111 to 120 of about 4,830,735 (205)
The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario +3 more
wiley +1 more source
GATA3 is a critical transcription factor for many developmental processes. During T helper (Th) cell differentiation, GATA3 induces the Th2 and suppresses the Th1 pathway.
Orly Avni, Eyal J Scheinman
core
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Progestin-mediated regulation of the transcription factor GATA3, and its involvement in breast cancer cell proliferation [PDF]
El factor de transcripción maestro GATA3 se encuentra involucrado en el desarrollo de la glandula mamaria y es requerido para el mantenimiento del estado diferenciado de las células epiteliales luminales.
Izzo, Franco
core +1 more source
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen +7 more
wiley +1 more source
LncRNA GATA3-AS1 promotes allergic rhinitis by regulating the miR-488-3p/NFIA axis
Background The pathogenesis of allergic rhinitis (AR) is affected by a combination of genetic and environmental factors. Objectives This study aimed to investigate the potential mechanisms of long non-coding RNA GATA binding protein 3 antisense RNA 1 ...
Xin Zhang, Taotao Lu, Rui Li
doaj +1 more source
Immunohistochemical expression of GATA3 in urothelial carcinoma of urinary bladder
Background and objective: GATA3, an emerging immunohistochemical marker, is a zinc finger transcription factor that is expressed in normal urothelial epithelium and its corresponding neoplasms, and it has been recognized as a reliable urothelial related ...
Shadan Abdulkhaliq Jaf, Jalal Ali Jalal
doaj +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
Expression Patterns of GATA3 in Classical Hodgkin Lymphoma: A Clinico-Pathological Study
GATA3 is a transcription factor involved in T-cell maturation and has been previously shown to be aberrantly overexpressed in malignant Hodgkin and Reed–Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL).
Alexandra Papoudou-Bai +4 more
doaj +1 more source
Females Display Greater Disease Severity in a Mouse Model of Vitiligo
We compared depigmentation in vitiligo‐prone, h3TA2 mice among males and females, and explored the effects of treatment with HSP70iQ435A plasmid DNA, delivered by biolistic administration. Mice shown from each cohort exemplify increased depigmentation among female mice and the treatment benefit of HSP70iQ435A. ABSTRACT Vitiligo is an autoimmune disease
Kaitlyn G. O'Donnell +12 more
wiley +1 more source

