Results 181 to 190 of about 37,179 (261)

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Protocol for haplotype-resolved genome comparison and allele-specific expression analysis across multiple tissues and individuals. [PDF]

STAR Protoc
Shi C, Liu S.
europepmc   +1 more source

Integrated Genome‐Wide Association Studies and Selection Signature Analysis Reveal the Genetic Architecture of the Wattle Trait in Goats

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Wattles are finger‐like appendages on the ventral neck of goats, serving as a distinctive morphological marker for breed identification that serves potential implications for production performance. However, their genetic basis remains incompletely characterized.
Siyi Hu, Chen Wei, Da Feng, Shangquan Gan   +3 more
wiley   +1 more source

Variant calling in genomics: A comparative performance analysis and decision guide. [PDF]

PLoS One
Pinto V, Sousa L, Silva C.
europepmc   +1 more source

A Combination of Alleles in LMOD2 and a lncRNA is Strongly Associated With Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT A previous genome‐wide association study identified regions on canine chromosome (cfa) 13 and 14 associated with early onset myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS). In the present study, whole genome sequencing (WGS) of 9 CKCS cases (mitral regurgitation (MR) before 4.5 years or congestive heart failure
Lisbeth Høier Olsen, Arney Eva Gunnlaugsdóttir, Majbritt Busk Madsen, Isabella Jane Larsen, Maria Josefine Ubbe Reimann, Foteini Papadaki, Ingrid Ljungvall, Jens Häggström, Torben Martinussen, Henrik Duelund Pedersen, Torkel Falk, Merete Fredholm, Peter Karlskov‐Mortensen   +12 more
wiley   +1 more source

Inferring the Landscapes of Mutation and Recombination in the Common Marmoset (Callithrix jacchus) in the Presence of Twinning and Hematopoietic Chimerism

American Journal of Primatology, Volume 88, Issue 10, October 2026.
Using high‐quality population genomic data, Soni, Versoza and colleagues infer the rates and landscapes of mutation and recombination in the common marmoset (Callithrix jacchus)—two fundamental processes dictating the levels and patterns of genetic variability—within the context of two biological peculiarities related to the reproductive mode of the ...
Vivak Soni, Cyril J. Versoza, Jeffrey D. Jensen, Susanne P. Pfeifer   +3 more
wiley   +1 more source

Aggregate variant calling using short reads enables population and disease studies for paralogous genes. [PDF]

HGG Adv
Prodanov T, Byun SY, Bansal V.
europepmc   +1 more source

Association of HRD Score With Efficacy of Neoadjuvant Short‐Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Homologous recombination deficiency (HRD) has been reported to be associated with increased sensitivity to platinum‐based treatment and radiotherapy in some solid tumors. Aim This study investigated the correlation between HRD score and treatment response to neoadjuvant short‐course radiotherapy combined with sequential chemotherapy
Xin Ran, He Xiao, Peng Zhou, Juan He, Mengyuan Si, Xiuqiong Chen, Xiaona Su, Zhuo Chen, Jia Du, Xiaoyan Dai, Xiao Yang, Haode Shen, Zongsheng He, Fan Li, Mengxia Li, Chuan Chen   +15 more
wiley   +1 more source

How precise are mutation rate estimates? Comparison of different approaches to estimate de novo mutation rates. [PDF]

Heredity (Edinb)
Wang X, Zhang C, Wang H, Reid K, Merilä J.   +4 more
europepmc   +1 more source

Whole‐Exome Sequencing Reveals the Genetic Landscape and Genotype–Phenotype Spectrum of Dystonia in a Chinese Cohort

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Whole‐exome sequencing of 147 Chinese patients with dystonia revealed an overall molecular diagnostic yield of 33.3%, with higher yields in generalized and childhood‐onset cases. The study expands the genotype–phenotype spectrum of established dystonia genes and provides population‐specific evidence to support genetic evaluation and molecular ...
Yiqing Gong, Huirong Peng, Zhao Chen, Jiawei He, Linliu Peng, Qian Jiang, Chunrong Wang, Linlin Wan, Lang He, Yuting Shi, Rong Qiu, Hong Jiang   +11 more
wiley   +1 more source