Results 61 to 70 of about 584,458 (264)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Gauge Theories and Holisms [PDF]

open access: yes, 2004
Those looking for holism in contemporary physics have focused their attention primarily on quantum entanglement. But some gauge theories arguably also manifest the related phenomenon of nonseparability.
Healey, Richard
core  

Remarks on quiver gauge theories from open topological string theory [PDF]

open access: yes, 2010
We study effective quiver gauge theories arising from a stack of D3-branes on certain Calabi-Yau singularities. Our point of view is a first principle approach via open topological string theory.
Carqueville, N.   +3 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Symplectic reduction and the problem of time in nonrelativistic mechanics [PDF]

open access: yes, 2010
Symplectic reduction is a formal process through which degeneracy within the mathematical representations of physical systems displaying gauge symmetry can be controlled via the construction of a reduced phase space. Typically such reduced spaces provide
Thebault, Karim P Y   +2 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

The absence of global anomalies of CP symmetry

open access: yesJournal of High Energy Physics
Some solutions to the strong CP problem assume that CP symmetry is a gauge symmetry, which is then spontaneously broken. For this scenario to be possible, the CP symmetry should not have any nonperturbative (global) anomalies.
Kazuya Yonekura
doaj   +1 more source

Automorphism in gauge theories: Higher symmetries and transversal non-Clifford logical gates

open access: yesSciPost Physics
Gauge theories are important descriptions for many physical phenomena and systems in quantum computation. Automorphism of gauge group naturally gives global symmetries of gauge theories.
Po-Shen Hsin, Ryohei Kobayashi
doaj   +1 more source

Gravity and Gauge [PDF]

open access: yes, 2012
Philosophers of physics and physicists have long been intrigued by the analogies and disanalogies between gravitational theories and (Yang-Mills-type) gauge theories.
Teh, Nicholas
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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