Results 11 to 20 of about 25,632 (110)

Gb3/cd77 Is a Predictive Marker and Promising Therapeutic Target for Head and Neck Cancer

open access: yesBiomedicines, 2022
Head and neck squamous cell carcinoma is the sixth leading cancer in the world. This cancer is difficult to treat and is characterized by recurrences that are often fatal.
L. García‐Hevia   +6 more
semanticscholar   +1 more source

The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3

open access: yesCommunications Biology, 2022
Choanoflagellates are primitive protozoa used as models for animal evolution. They express a large variety of multi-domain proteins contributing to adhesion and cell communication, thereby providing a rich repertoire of molecules for biotechnology ...
Simona Notova   +11 more
semanticscholar   +1 more source

Optical Manipulation of Gb3 Enriched Lipid Domains: Impact of Isomerization on Gb3‐Shiga Toxin B Interaction

open access: yesChemistry, 2022
The plasma membrane is a complex assembly of proteins and lipids that can self‐assemble in submicroscopic domains commonly termed “lipid rafts”, which are implicated in membrane signaling and trafficking.
Larissa Socrier   +5 more
semanticscholar   +1 more source

A pore-forming β-trefoil lectin with specificity for the tumor-related glycosphingolipid Gb3

open access: yesbioRxiv, 2022
Lectins are efficient multivalent glycan receptors, deciphering the glyco-code on cell surfaces. The β-trefoil fold, characterized by three lobe-shaped repeats, is adopted by several classes of lectins, often associated with other domains having ...
Simona Notova   +9 more
semanticscholar   +1 more source

Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3

open access: yesFrontiers in Molecular Biosciences, 2021
Glycolipids are present on the surfaces of all living cells and thereby represent targets for many protein receptors, such as lectins. Understanding the interactions between lectins and glycolipids is essential for investigating the functions of lectins ...
Lina Siukstaite, A. Imberty, W. Römer
semanticscholar   +1 more source

RIPK3 Contributes to Lyso-Gb3-Induced Podocyte Death

open access: yesCells, 2021
Fabry disease is a lysosomal storage disease with an X-linked heritage caused by absent or decreased activity of lysosomal enzymes named alpha-galactosidase A (α-gal A).
So-Young Kim   +10 more
semanticscholar   +1 more source

Island, Identity, and Trauma: The Three Ecologies of Wu Ming-Yi's 'the Man With the Compound Eyes'

open access: yesIsland Studies Journal, 2023
Following Ivakhiv's tri-ecological perspective, we undertake an analysis of Wu Ming-Yi's ecological science fiction *The Man with the Compound Eyes*, which skillfully delineates a multi-faceted, three-dimensional network of island ecology via ...
Kunyu Wang, Guidan Zhang, Lucy Drummond
doaj   +1 more source

Mountain height as a proxy for the cessation of active plate convergence

open access: yesGeosystems and Geoenvironment, 2023
Megathrust shear force along convergent plate margins exerts a primary control on the height/elevation of mountain ranges, which can be mechanically sustained.
Raja Sen   +3 more
doaj   +1 more source

Missing the sweet spot: one of the two N-glycans on human Gb3/CD77 synthase is expendable

open access: yesbioRxiv, 2021
N-glycosylation is a ubiquitous posttranslational modification that may influence folding, subcellular localization, secretion, solubility and oligomerization of proteins.
Krzysztof Mikołajczyk   +13 more
semanticscholar   +1 more source

Потенціал природних рекреаційно-туристичних ресурсів для формування туристичної привабливості території Гадяцької територіальної громади Полтавської області [PDF]

open access: yesНаукові записки Сумського державного педагогічного університету ім. А.С. Макаренка. Географічні науки
У статті визначено класифікації та властивості природних рекреаційно-туристичних ресурсів. З’ясовано потенціал водно-ландшафтних ресурсів Гадяччини для забезпечення оздоровчого та рекреаційно-спортивного туризму. Проаналізовано кліматичні умови території
Мащенко О.М.   +1 more
doaj   +1 more source

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