Results 11 to 20 of about 19,114 (240)

Three-Dimensional Motion Compensation Method Based on Sparse Array Designed for Time-Division Multiplexing Multiple-Input-Multiple-Output Through-Wall Radar

open access: yesApplied Sciences, 2023
A large-aperture radar composed of a multiple-input-multiple-output (MIMO) planar array can complete 3D through-wall imaging (TWI), but the simultaneous work of the multiple transceiver channels leads to difficulties in designing the hardware.
Jun Pan   +8 more
doaj   +1 more source

Cognitive Functioning of Glucocerebrosidase (GBA) Non-manifesting Carriers

open access: yesFrontiers in Neurology, 2021
Mutations and variants in the glucocerebrosidase (GBA) gene are among the most common genetic risk factors for the development of Parkinson's disease (PD).
Eileen E. Moran   +21 more
doaj   +1 more source

Indonesian EFL teachers

open access: yesJournal on English as a Foreign Language, 2023
Many studies indicated a genre-based approach (GBA) as an effective method in English foreign language (EFL) teaching and GBA is also integrated into the English teaching curriculum.
Nurfadilah Nadjib, Anita Triastuti
doaj   +1 more source

Synuclein Disorder-Related Genetic Determinants of Mild Behavioural Impairment in a Pre-Clinical Community Cohort. [PDF]

open access: yesInt J Geriatr Psychiatry
ABSTRACT Background The GBA variant confers increased risk of synuclein disorders but it is unclear what impact it has in pre‐clinical groups. This study aimed to identify early psychiatric and cognitive manifestations amongst pre‐clinical GBA carriers in a community cohort.
Sander-Long M   +5 more
europepmc   +2 more sources

Performance-Optimizing Secure GBAS Over LDACS [PDF]

open access: yes2021 Integrated Communications Navigation and Surveillance Conference (ICNS), 2021
VHF Data Broadcast (VDB) currently used by GBAS has been identified as a potential source of cyber-security concerns. The use of an alternative datalink providing the bandwidth for more capable security protocols has therefore been proposed and demonstrated on the basis of the L-band Digital Aeronautical Communication System (LDACS). However, the first
Gräupl, Thomas, Mäurer, Nils
openaire   +2 more sources

Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease

open access: yesnpj Parkinson's Disease, 2022
The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greater ...
Rosie Morris   +16 more
doaj   +1 more source

Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2

open access: yesMolecular Brain, 2021
Lysosomal dysfunction is a central pathway associated with Parkinson’s disease (PD) pathogenesis. Haploinsufficiency of the lysosomal hydrolase GBA (encoding glucocerebrosidase (GCase)) is one of the largest genetic risk factors for developing PD ...
Ria Thomas   +4 more
doaj   +1 more source

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein. [PDF]

open access: yesPLoS Genetics, 2015
Homozygous mutations in the glucocerebrosidase (GBA) gene result in Gaucher disease (GD), the most common lysosomal storage disease. Recent genetic studies have revealed that GBA mutations confer a strong risk for sporadic Parkinson's disease (PD).
Norihito Uemura   +12 more
doaj   +1 more source

Reduced expression of neurogenesis genes as biomarkers of Parkinson's disease associated with mutations in the GBA gene: validation of the data analysis of transcriptome study

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
The objective of the study was to validate our previous results obtained during the transcriptome analysis of the primary culture of peripheral blood macrophages in patients with Parkinson's disease associated with mutations in the GBA gene (GBA-PD) in ...
A. I. Bezrukova   +6 more
doaj   +1 more source

Association of GBA genotype with motor and cognitive decline in Chinese Parkinson’s disease patients

open access: yesFrontiers in Aging Neuroscience, 2023
ObjectiveVariants in the glucocerebrosidase (GBA) gene are the most common and significant risk factor for Parkinson’s disease (PD). However, the impact of GBA variants on PD disease progression in the Chinese population remains unclear. This study aimed
Jingru Ren   +10 more
doaj   +1 more source

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