Results 211 to 220 of about 204,238 (313)

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Design of a Six Degrees of Freedom Force/Torque Platform

Measurement + Control, 1991
J P Micallef, C Valentin, I Tadjou, R Quatrefages, P Arfos   +4 more
doaj   +1 more source

The Invasive Margin of Glioblastoma as a Molecular Ecosystem: Spatial Heterogeneity, Tumor-Host Interactions, and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Kuczyński N, Larysz D, Uchman-Rzeżnik D, Irianto G, Pilewski D.   +4 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Glioblastoma in adults with prior extracranial cancer: a Czech retrospective multicentre study. [PDF]

Front Oncol
Kalita O, Kazda T, Tomoszkova S, Jancalek R, Slachta M, Fric D, Krejci T, Kourilova P, Cvek J, Dolezel M, Hrabalek L, Lipina R.   +11 more
europepmc   +1 more source

Data‐Driven Prediction of Block Copolymer Morphology Using Coarse‐Grained Modeling and Machine Learning

Journal of Polymer Science, EarlyView.
An integrated framework combining high‐throughput CG‐MD simulations, automated image‐based feature extraction, and supervised machine learning enables efficient, interpretable, and data‐driven prediction of block copolymer morphological behaviors.
Lan Xu, Zhaofan Li, Wenjie Xia
wiley   +1 more source

Effects of proton therapy on the tumor immune system and clinical implications: A review

Precision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu, Mei Tao, Min Fu, Yingjia Hu, Zhen Tao, Guangyuan Hu   +5 more
wiley   +1 more source

Lipid metabolic plasticity in glioblastoma: mechanisms, tumor microenvironment remodeling, and therapeutic opportunities. [PDF]

Front Oncol
Wu W, Liu M, Lv Q, Ming Z, Song L, Chu J.   +5 more
europepmc   +1 more source

Bacterial-type endochitinases of fungal entomopathogens and mycoparasites

, 2008
Guzalova, A.G., Schairer, H.U., Leclerque, A., Ergashev, K.   +3 more
core  

Rest‐frame statistics of 32 GBM‐GRBs

, 2011
von Kienlin, A., Olivares, F., Gruber, D., Greiner, J., Rau, A.   +4 more
core   +1 more source