Results 221 to 230 of about 204,238 (313)

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

The Unsaturated/Saturated Fatty Acid Ratio: A Metabolic Hub and Therapeutic Vulnerability in Glioblastoma. [PDF]

Biomedicines
Dai X, Ku J, Li H, Yan R, Wang B.
europepmc   +1 more source

Brassinin Inhibits Cell Survival and Autophagy via Modulation of ROS Production and the AMPKα‐beclin1 Signaling Pathway in Gliomas

Phytotherapy Research, EarlyView.
Brassinin, a phytoalexin derived primarily from Chinese cabbage, exhibits potent anticancer activity against glioblastoma (GBM). Mechanistically, brassinin treatment elevates intracellular ROS levels in GBM cells, triggering two parallel outcomes: (i) direct induction of apoptosis, and (ii) suppression of cytoprotective autophagy through downregulation
Sunil Rauniyar, Yuhui Wang, Qiaoshan Zhang, Shicheng Zhang, Jiale Yin, Tong Zhang, Shangfeng Gao, Rutong Yu   +7 more
wiley   +1 more source

miR-152-3p Overcomes Temozolomide Resistance in Glioblastoma by Targeting TGF-α and Enhancing Apoptosis. [PDF]

Oncol Res
Chao CN, Fang CY, Hou CH, Yang JT, Wu YP, Chen JC.   +5 more
europepmc   +1 more source

How AI and Digital Technologies Can Enhance Sustainable Livestock Manure Management: An Overview From Treatment to Distribution

Sustainable Development, EarlyView.
ABSTRACT Sustainable livestock manure management sits at the nexus of climate, nutrient circularity and water quality. This review explores how artificial intelligence (AI) and digital platforms are used across four management stages, that is, treatment, storage, valorisation and distribution, and figures out where integration fails to deliver ...
Zhan Shi, Feihong Liang, Francesco Marinello, Andrea Pezzuolo   +3 more
wiley   +1 more source

Beyond the Brain: Circulating Tumor Cells as a Tool for Diagnosis and Monitoring. [PDF]

JCO Precis Oncol
Lessi F, Morelli M, Di Gangi A, Franceschi S, Di Lorenzo F, Sandro C, Aretini P, Pastore A, Ferri G, Menicagli M, Pasqualetti F, Gambacciani C, Villanacci F, Zucchi V, Cupini S, Di Stefano AL, Santonocito OS, Mazzanti CM.   +17 more
europepmc   +1 more source

Deepening the real options debate: Real options as dynamic optimization

Strategic Management Journal, EarlyView.
Abstract Research Summary Is real option theory useful for management research? This topic was hotly debated two decades ago. Real options were said to be inapplicable to management research and to lack conceptual distinctiveness. Whereas responses to the claim about the non‐distinctiveness of real options were disparate, the concern about the theory's
Arkadiy V. Sakhartov, Joseph T. Mahoney, Jeffrey J. Reuer   +2 more
wiley   +1 more source

HIV Pre-Exposure Prophylaxis Use Among South Asian Sexual Minority Men in the United States: Pilot Web-Based Survey Study. [PDF]

JMIR Form Res
Sharma A, Boyd S, Sallabank G.
europepmc   +1 more source

Direct Growth of BODIPY‐Based Conjugated Porous Polymer Shell on Upconversion Nanoparticles for NIR‐Driven Photocatalysis

Small, EarlyView.
Monomer prefunctionalization of upconversion nanoparticles directs uniform growth of BODIPY‐based conjugated porous polymers shells, affording precise control over polymer loading and optimized NIR‐triggered photocatalytic activity. ABSTRACT The great applications of upconversion nanoparticles (UCNPs) can be further extended by their encapsulation ...
Teresa Naranjo, Laura Francés‐Soriano, Delia Bellezza, Julia Pérez‐Prieto, Víctor A. de la Peña O´Shea, Marta Liras, María González‐Béjar   +6 more
wiley   +1 more source

Enhanced Glioblastoma Targeting and Penetration: Extracellular Matrix Remodeling by Collagenase-Functionalized Ferumoxytol Nanoparticles. [PDF]

Nano Lett
Wang J, Annio G, Duwa R, Suryadevara V, Chang E, Daldrup-Link H.   +5 more
europepmc   +1 more source