Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai +18 more
wiley +1 more source
Gas Chromatography-Mass Spectrometry (GC-MS) in the Plant Metabolomics Toolbox: GC-MS in Multi-Platform Metabolomics and Integrated Multi-Omics Research. [PDF]
Frolova N +5 more
europepmc +1 more source
خوباننامه (MS 174); زنان نامه (MS 175); رقاص نامه (MS 176)
Bu cilt, birbirinden farklı 3 yazmanın bir araya getirilmesiyle oluşturulmuştur (Yazma numaraları : MS 174, MS 175, MS 176). Üç eser de Osmanlıca yazılmıştır. MS 174, 1792 yılına tarihlenirken, diğer iki yazmanın kaleme alınma tarihi bilinmemektedir.
Enderunlu Fazıl [d. 1225 / 1810] / فاضل اندرونى (MS 174, MS 175, MS 176)
core
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Phthalates and Mixed Alkyl Phthalates Analysis in Plastics Using GC-MS With Cold EI. [PDF]
Elkabets O, Neumark B, Amirav A.
europepmc +1 more source
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang +13 more
wiley +1 more source
QuEChERS-GC-MS/MS Analysis of Multi-Class Pesticide Residues in Tropical Agricultural Soils. [PDF]
Riaño-Herrera DA +5 more
europepmc +1 more source
Synergy of Pd Clusters and TiO2 {101} for Photocatalytic Nonoxidative Coupling of Methane
This study presents photocatalytic nonoxidative coupling of methane over cal‐Pd0.05/TiO2{101}, achieving near 100% selectivity and long‐term stability under mild flow conditions through synergistic single atoms and clusters catalysis. ABSTRACT Photocatalytic nonoxidative coupling of methane (NOCM) offers a sustainable route to valorize CH4 into C2 ...
Jianlong Yang +2 more
wiley +1 more source
Refined analysis of microplastics in endemic fish species from Lake Victoria using µ-FTIR and pyrolysis GC-MS. [PDF]
Omara T +8 more
europepmc +1 more source

