Results 11 to 20 of about 14,116 (173)
Characteristics of Glycemic Variability in Patients with GCK-MODY
Архивъ внутренней медицины, 2022 GCK-MODY is one of the most common MODY variants (40–60 %) in the European population. It is possible to use continuous glucose monitoring systems (CGMS) when diagnosing GCK-MODY which allows for an analysis of glucose variability (GV) using mathematical
A. K. Ovsyannikova +3 more
doaj +3 more sources
An evolving spectrum of diabetes in a woman with GCK-MODY [PDF]
Endocrinology, Diabetes & Metabolism Case Reports, 2019 Coexistence of autoimmune diabetes and maturity-onset diabetes of the young (MODY) is rare. We report the first case of coexisting latent autoimmune diabetes of adulthood (LADA) and glucokinase (GCK) MODY. A 32-year-old woman was treated with insulin for
Aoife Garrahy +2 more
doaj +4 more sources
GCK-MODY diabetes course in persons over 18 years of age: prospective observation [PDF]
Сахарный диабет, 2021 Most young patients with hyperglycemia have type 1 diabetes and type 2 diabetes but up to 10% of all cases of the disease occur in MODY (Maturity Onset Diabetes of the Young).
A. K. Ovsyannikova +4 more
doaj +2 more sources
Quality of life assessment in patients with HNF1A-MODY and GCK-MODY. [PDF]
Endocrine, 2019 Aim: The impact of maturity onset diabetes of the young (MODY) on quality of life (QoL) has never been examined. We assessed disease impact on QoL among patients with HNF1A-MODY and GCK mutation carrier status.
Szopa M +11 more
europepmc +6 more sources
Incidence of HNF1A and GCK MODY Variants in a South African Population [PDF]
The Application of Clinical Genetics, 2020 Tandi E Matsha,1,* Shanel Raghubeer,1,* Abegail M Tshivhase,1 Saarah FG Davids,1 Gloudina M Hon,1 Lise Bjørkhaug,2 Rajiv T Erasmus1 1SAMRC/Cardiometabolic Health Research Unit, Department of Biomedical Sciences, Faculty of Health & Wellness ...
Matsha TE +6 more
doaj +4 more sources
Incidence of HNF1A and GCK MODY Variants in a South African Population. [PDF]
Appl Clin Genet, 2020 Background and Aim: Maturity-onset diabetes of the young (MODY) is the result of single gene variants. To date, fourteen different MODY subtypes have been described. Variants in genes coding for glucokinase (GCK, MODY2) and hepatic nuclear factor 1 alpha
Matsha TE +6 more
europepmc +6 more sources
Evaluation of pregnancy outcomes in women with GCK-MODY
Diabetic Medicine, 2021 Aims: To determine the fetal and maternal outcomes in pregnant women with Glucokinase-Maturity onset diabetes of the young (GCK-MODY). Methods: We studied the obstetric and perinatal outcomes in 99 pregnancies of 34 women with GCK-MODY.
Colclough, Kevin
core +4 more sources
Hypoglycemic response to dorzagliatin in a patient with GCK-MODY
Diabetes CareOBJECTIVEMetformin, insulin, and insulin secretagogues do not alter HbA1c levels in glucokinase-maturity-onset diabetes of the young (GCK-MODY). However, the efficacy of the new hypoglycemic drugs on GCK-MODY remains unclear.RESEARCH DESIGN AND METHODSWe
Tianhao Ba (14802617) +5 more
core +3 more sources
Chronic Mild Hyperglycemia in GCK-MODY Patients Does Not Increase Carotid Intima-Media Thickness [PDF]
International Journal of Endocrinology, 2013 Aim. GCK-MODY is an autosomal dominant form of diabetes caused by heterozygous mutations in the glucokinase gene leading to a lifelong mild hyperglycemia. The risk of macrovascular complications is considered low, but studies are limited.
Stepanka Pruhova +11 more
doaj +2 more sources
A novel genetic mutation in a Turkish family with GCK-MODY
International Journal of Diabetes in Developing Countries, 2017 Glucokinase-maturity-onset diabetes of the young (GCK-MODY) is an autosomal dominantly inherited disease caused by heterozygous inactivating mutations in the glucokinase gene. It usually presents with mild fasting hyperglycemia. Here, we present an obese
Mengen E. +5 more
core +3 more sources