Results 81 to 90 of about 28,531 (210)
Pre‐treatment of grapevine plants with oregano essential oil vapour alleviates downy mildew susceptibility by accumulation of monoterpenol glycosides. Abstract Grapevine downy mildew, caused by the oomycete Plasmopara viticola, is a destructive disease that causes major economic losses as most elite grapevine cultivars are susceptible to this pathogen.
J. R. P. E. Mars +6 more
wiley +1 more source
This review synthesizes discussions from the 2025 International CMV Symposium on translating three recently updated international guidelines into clinical practice across solid organ and hematopoietic stem cell transplantation, highlighting advances in risk‐stratified prevention, emerging therapies, immune monitoring, and persistent implementation ...
Camille N. Kotton +3 more
wiley +1 more source
GCV phosphates are transferred between HeLa cells despite lack of bystander cytotoxicity [PDF]
The role of gap junctional intercellular communication (GJIC) in bystander killing with herpes simplex virus thymidine kinase (HSV-TK) and ganciclovir (GCV) was evaluated in U251 cells expressing a dominant-negative connexin 43 cDNA (DN14), and in HeLa cells, reportedly devoid of connexin protein. These cell lines both exhibited 0% GJIC when assayed by
B G, Gentry +4 more
openaire +2 more sources
Efficacy and safety of a fixed low‐power, long‐duration radiofrequency catheter ablation of ventricular arrhythmias originating from the left ventricular summit. ABSTRACT Background Radiofrequency catheter ablation (RFCA) of ventricular arrhythmias originating from the left ventricular summit (LVS‐VAs) remains challenging.
Takuro Masuda +10 more
wiley +1 more source
Purpose. To evaluate the safety and pharmacokinetic changes of ganciclovir (GCV) intraocular injection. Methods. GCV (2 mg/0.1 mL) was injected into rabbit eyes. Aqueous GCV concentration was detected by high-performance liquid chromatography.
Bin-jia Sun +3 more
doaj +1 more source
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche +8 more
wiley +1 more source
CSGM: A R Package to Conduct a Robust Cross‐Sectional Geometric Morphometric Analysis
ABSTRACT Objective Evaluating the relationships between the shape and biomechanical function of bone cross‐sections can contribute novel insights towards human functional and evolutionary morphology. However, this research involves unique analytical and statistical challenges when comparing complex and multidimensional shape data to multivariate ...
Brian A. Keeling +5 more
wiley +1 more source
Global and local distance-based generalized linear models [PDF]
This paper introduces local distance-based generalized linear models. These models extend (weighted) distance-based linear models first to the generalized linear model framework. Then, a nonparametric version of these models is proposed by means of local
Boj, Eva +4 more
core +1 more source
Health Prognostics in Multi‐Sensor Systems Based on Multivariate Functional Data Analysis
ABSTRACT Recent developments in big data analysis, machine learning, Industry 4.0, and IoT applications have enabled the monitoring and processing of multi‐sensor data collected from systems, allowing for the prediction of the “Remaining Useful Life” (RUL) of system components.
Cevahir Yildirim +2 more
wiley +1 more source
【目的】探讨腺病毒介导单纯疱疹病毒胸苷激酶基因(AdCMVHSV-TK)/ 丙氧鸟苷(GCV)自杀基因系统对口腔 鳞癌移植瘤的治疗作用。【方法】Tca8113 细胞接种于裸鼠右侧腋下, 移植瘤形成时随机分成4 组:①空白对照组, ②Ad- CMVHSV-TK 对照组(2×109 PFU, 瘤内注射), ③GCV 对照组(25 mg/ kg , Bid ×6, 腹腔注射), ④AdCM VHSV-TK/ GCV 治疗 组, 并开始治疗。观察肿瘤的生长状态、计算抑瘤率和肿瘤群体倍增时间 ...
黄洪章, 王安训, 李 苏
doaj

