Results 71 to 80 of about 732,678 (244)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Italian Journal of Medicine, 2014 In the past, anaerobes were the most common cause of community-acquired lung abscess; Streptococcus species were the second most common cause. In recent years, this has changed.
Alessandro Perazzo +7 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Meaning of folk and artistic knowledge for education in biodiversity preservation
Agrisost, 2016 The aim of this paper is to provide a theoretical background to the meaning of folk and artistic knowledge for education in biodiversity preservation, from natural and agricultural sciences, and its effect on teacher training in these specialties.
Marisela Guerra Salcedo +1 more
doaj
A memory based model for cartilage and meniscus segmentation in 3D knee MRI
Scientific ReportsAccurate morphometric assessment of cartilage—such as thickness and volume—via MRI is essential for monitoring knee osteoarthritis. However, segmenting cartilage remains challenging and dependent on extensive expert-annotated datasets, which are heavily ...
Danielle L. Ferreira +5 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Corrosion behavior of additively manufactured FeCrAl in out-of-pile light water reactor environments
npj Materials DegradationIron-Chromium-Aluminum (FeCrAl) alloys are candidate materials for the cladding of light water reactor (LWR) fuels. The FeCrAl alloys in general range in Cr composition from 12% (C26M) to 21% (APMT).
Rajnikant V. Umretiya +8 more
doaj +1 more source
Using Ontology to Drive an Adaptive Learning Interface [PDF]
Journal of Systemics, Cybernetics and Informatics, 2004 Intelligent, adaptive interfaces are a pre-requisite to elevating computer-based applications to the realm of collaborative decision support in complex, relatively open-ended domains such as logistics and planning.
Andrew Crapo +3 more
doaj
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source