Results 141 to 150 of about 92,725 (287)

Cellulose-Derived Gels for Topical Delivery: HPMC as a Functional Matrix for Porphyrinic Photosensitizers

open access: yes
Hydroxypropyl methylcellulose (HPMC) is a biocompatible polymer widely used in topical formulations due to its suitable rheological behavior, film-forming capacity, and good compatibility with different active pharmaceutical ingredients.
Adina Magdalena Musuc   +13 more
core   +1 more source

Formulation development and evaluation of Diclofenac sodium gel using water soluble polyacrylamide polymer

open access: yes, 2020
High molecular weights water soluble homopolymer of acrylamide are reported to possess very high viscosity in low concentration, transparency, film forming properties and are useful in formation of gel.
A A Roy Sharad   +4 more
core  

EVALUASI, UJI STABILITAS FISIK DAN SINERESIS SEDIAAN GEL YANG MENGANDUNG MINOKSIDIL, APIGENIN DAN PERASAN HERBA SELEDRI (Apium graveolens L.)

open access: yes, 2015
Minoxidil, apigenin and celery are believed to have the same bioactivity as a vasodilator that can widen blood vessels. This study discusses about the gel formulation in the scope of evaluation of gel preparation, using carbomer as a gelling agent each ...
Kuncari, Emma Sri; Fakultas Farmasi UI, Kampus UI Depok 16424 Puslit Biologi LIPI, Jl. Raya Jakarta-Bogor Km. 46 Cibinong 16911 Indonesia   +2 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Identification of candidate genes for gelatinization temperature, gel consistency and pericarp color by GWAS in rice based on SLAF-sequencing. [PDF]

open access: yesPLoS One, 2018
Yang X   +10 more
europepmc   +1 more source

(32(1):14-22)Improvement of Grain Quality in Rice-II. Genetical Studies on Gel Consistency and Amylose Content

open access: yes, 2010
本研究使用嘉農秈11 號× 臺農67 號及臺南5 號× 臺中在來1 號等兩個秈稉異型稻間之雜交F2集團為材料,測定各單株米粒之顆粒澱粉含量及膠體硬度等兩個主要食用品質性狀,以闡述秈稉雜交後代米粒食用品質之遺傳行為,結果獲知: 1. 兩雜交組合F2集團膠體硬度之頻度分布為具尖峰之偏歪分布,且均可分成3 高硬度:1 低硬度之比例,符合孟德爾氏單性雜種分離之遺傳理論。 2.
Sung-Ching Hsieh   +3 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

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