Results 101 to 110 of about 1,156,214 (332)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Insight of Saffron Proteome by Gel-Electrophoresis

Molecules, 2016
Saffron is a spice comprised of the dried stigmas and styles of Crocus sativus L. flowers and, since it is very expensive, it is frequently adulterated.
Gianluca Paredi, Samanta Raboni, Francesco Marchesani, Stella A. Ordoudi, Maria Z. Tsimidou, Andrea Mozzarelli   +5 more
doaj   +1 more source

Separation of Metastable Polymers by Starch Gel Electrophoresis [PDF]

, 1958
Geoffrey Franglen, CÉCILE GOSSELIN
openalex   +1 more source

Biologic activity in a fragment of recombinant human interferon α [PDF]

, 1984
To attempt to locate functionally important regions of the interferon (IFN) molecule, recombinant human IFN-α2 was subjected to proteolytic digestion. The bacterial proteinase thermolysin produced two major complementary fragments, HuIFN-α2-(1-110) and ...
Ackerman, Samuel K., Heintzelman, Mark, Hunkapiller, Michael, Zoon, Kathryn, Zur Nedden, Dorothy   +4 more
core  

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Agarose gel electrophoresis: Applications in clinical chemistry [PDF]

Journal of Medical Biochemistry, 2010
Agarose gel electrophoresis is a well established technique routinely used in clinical laboratories for screening protein abnormalities in various biological fluids (serum, urine, CSF).
Giot Jean-Francois
doaj  

An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals [PDF]

, 1959
Oliver Smithies
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Gel Diffusiophoresis of a Spherical Colloidal Particle

Fluids
A theoretical framework is established for the gel diffusiophoresis of a spherical colloidal particle moving through an uncharged dilute porous polymer gel medium when an electrolyte concentration gradient field is applied.
Hiroyuki Ohshima
doaj   +1 more source

Analysis of Proteins of Bovine Lens, Vitreous, and Aqueous by Electrophoresis and by Oudin's Gel Diffusion Technique [PDF]

, 1955
S. S. Rao, MV Kulkarni, S.N. Cooper, M. R. Radhakrishnan   +3 more
openalex   +1 more source