TRANSFER RNA: A COMPARISON BY GEL ELECTROPHORESIS OF THE TRNA IN HELA CYTOPLASM, HELA MITOCHONDRIAL FRACTION, AND E. coli [PDF]
E. Knight, T. Sugiyama
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Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
The application of single cell gel electrophoresis or comet assay to human monitoring studies
Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods.
Valverde Mahara+7 more
doaj
Polyacrylamide gel electrophoresis: a versatile tool for the separation of nanoclusters. [PDF]
Packirisamy V, Pandurangan P.
europepmc +1 more source
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang+11 more
wiley +1 more source
Uncertainty Estimation for Quantitative Agarose Gel Electrophoresis of Nucleic Acids. [PDF]
Semenov K+6 more
europepmc +1 more source
Electrophoresis in Polyacrylamide Gels of Different ‘Soluble’ Ribonucleic Acid Preparations from Escherichia coli [PDF]
Mark Cannon, E. G. Richards
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Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski+3 more
wiley +1 more source
Agarose Gel Electrophoresis Reveals the Molecular Weight Distribution of Hyaluronan Produced by Orbital Fibroblasts. [PDF]
Galgoczi E+7 more
europepmc +1 more source