Results 201 to 210 of about 100,614 (290)

Transmembrane Transport of cAMP and AMP Using a Two Component Small Molecule Transport System

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Transmembrane transport of the nucleotides cAMP (cyclic adenosine monophosphate) and AMP (adenosine monophosphate) is challenging, but can be achieved using a two‐component system consisting of a synthetic anionophore (e.g., squaramides) and a lipophilic thymine derivative.
Uththara M.C. Rathnaweera, Olivia Sam, Karolis Norvaisa, Sarah R. Marshall, Randima D. De Silva Weerakonda Arachchige, Matúš Chvojka, Hennie Valkenier, Nathalie Busschaert   +7 more
wiley   +2 more sources

A Phase II Study of Toripalimab in Combination with Gemcitabine and 5-Fluorouracil as First-Line Therapy for Advanced or Metastatic Biliary Tract Carcinoma. [PDF]

Cancers (Basel)
Lei F, Deng W, Zhou Y, Fang L, Lin X, Qin L, Li C, Rao J, Yu G.   +8 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Case Report: Palliative chemotherapy with gemcitabine and carboplatin for carcinoma of unknown primary with metastasis in a cat. [PDF]

Front Vet Sci
Park HA, Kim K, Choi CH, Ro WB, Lee CM.
europepmc   +1 more source

Efficacy and safety of Anlotinib in combination with gemcitabine and cisplatin as a first‐line treatment for recurrent or metastatic nasopharyngeal carcinoma: A single‐arm clinical trial [PDF]

Zhehao Xiao, Weiling Chen, Youqin Du, Fanyan Zeng, Fang Su, Shi‐Ting Huang, Song Qu   +6 more
openalex   +1 more source

Long‐term outcomes of a cascading salvage strategy for high‐risk non‐muscle‐invasive bladder cancer

BJU International, Volume 137, Issue 2, Page 339-347, February 2026.
Objective To report long‐term oncological outcomes of patients with high‐risk non‐muscle‐invasive bladder cancer (HR‐NMIBC) undergoing bladder‐sparing therapy (BST) after bacillus Calmette–Guérin (BCG) failure. Patients and Methods We retrospectively reviewed patients with HR‐NMIBC treated from 2000 to 2025 with intravesical therapies after BCG failure,
Ian M. McElree, Ryan L. Steinberg, Helen Y. Hougen, Sarah L. Mott, Vignesh T. Packiam, Michael A. O'Donnell   +5 more
wiley   +1 more source

Radiotherapy in the management of PDAC, from past to present. [PDF]

Transl Oncol
Dardare J, Martz N, Witz A, Betz M, Michel C, Gilson P, Merlin JL, Lambert A, Harle A.   +8 more
europepmc   +1 more source

CUL2 confers ferroptosis resistance in pancreatic cancer by disrupting KEAP1-mediated NRF2 degradation. [PDF]

Cancer Cell Int
Yu K, Chen L, Zhong Y, Wang Y, Zhu N, Wang D, Yao W, Bai H, Yang L, Qi D.   +9 more
europepmc   +1 more source

Gemcitabine and docetaxel for high‐risk non‐muscle‐invasive bladder cancer: EuroGemDoce group results [PDF]

Pietro Scilipoti, Mattia Longoni, Mario de Angelis, Paolo Zaurito, Albane Massiet, Daniele Dutto, Francesco Soria, Mario Álvarez‐Maestro, Alfredo Aguilera Bazán, Benjamin Pradere, Tobias Klatte, Roberto Contieri, Rodolfo Hurle, Wojciech Krajewski, José Daniel Subiela, Renate Pichler, Aleksandra Szostek, Gautier Marcq, José Luis Rodríguez Elena, Javier Aranda, Paolo Gontero, Morgan Rouprêt, Shahrokh F Shariat, Andrea Necchi, Francesco Montorsi, Alberto Briganti, Évanguelos Xylinas, Marco Moschini, The EuroGemDoce Study Group Collaborators, Urothelial Carcinoma Working Group   +29 more
openalex   +1 more source

Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer. [PDF]

Cells
Ansardamavandi A, Dumesny C, Ellis S, Ang CS, Nikfarjam M, He H.   +5 more
europepmc   +1 more source