Results 201 to 210 of about 98,417 (285)

Camonsertib, an ATRi, in Combination with Low-Dose Gemcitabine in Solid Tumors with DNA Damage Response Aberrations: Preclinical and Phase Ib Results. [PDF]

Clin Cancer Res
Rosen EY, Yap TA, Fontana E, Lee EK, Mahalingam D, Højgaard M, Mettu NB, Cote GM, Plummer R, Koehler M, Ulanet D, Fei K, Silverman IM, Schonhoft JD, Rimkunas V, Bacque ES, Gomez G, Fretland AJ, Roulston A, Li L, Baruah P, Zimmermann M, Yang J, Carneiro BA, Lheureux S.   +24 more
europepmc   +1 more source

Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang, Tao Zhu, Xiaotong Hu, Zhinong Jiang, Hongchuan Jin   +4 more
wiley   +1 more source

Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Tumor‐derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in TDE‐mediated tumor progression in PC remains inadequately explored. Methods Ultracentrifugation was used to isolate exosomes derived from AsPC‐1 and
Xiangyu Chu, Dongqi Li, Fusheng Zhang, Yongsu Ma, Yongqi Deng, Chen Wang, Xiaodong Tian, Yanlian Yang, Yinmo Yang   +8 more
wiley   +1 more source

Efficacy and Toxicity in Scheduled Intravesical Gemcitabine Versus Bacillus Calmette-Guérin for Bladder Cancer: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel)
Kim DK, Jeon J, Kwon JK, Bang S, Lee KS, Koo KC, Cho KS.   +6 more
europepmc   +1 more source

NUP93 facilitates the nuclear import of SOX2 to activate G3BP1 transcription and impairs gemcitabine response in pancreatic cancer. [PDF]

Cell Death Dis
Sun H, Yang C, Du J, Xu C, Chen Y, Chen J, Yue N, Gong R, Yang Z.   +8 more
europepmc   +1 more source

Development of an Artificial Intelligence Web Application for Predicting Chemotherapy‐Induced Neutropenia in Patients With Non‐Small Cell Lung Cancer: A Prospective Study

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Objective This study aimed to develop an artificial intelligence (AI) web application for predicting chemotherapy‐induced neutropenia (CIN) in patients with non‐small cell lung cancer (NSCLC). Methods We conducted a prospective study including 310 patients who underwent 1047 chemotherapy cycles with NSCLC patients between 2019 and 2024 from ...
Jingyue Zhang, Yang Zhai, Chang Liu, Miaomiao Luo, Jiahui Liu, Qi Liu, Hanxu Zhang, Shijiao Cai, Ye Tian, Liangfu Lu, Linlin Zhang, Hengjie Yuan   +11 more
wiley   +1 more source

A next-generation multimetal complex induces immunogenic cell death with distinct transcriptomic signatures.

Chem Commun (Camb)
Babu T, Levine MS, Zeng B, Sessler JL.
europepmc   +1 more source

Durable Disease Control in Disseminated Primary Splenic Leiomyosarcoma Treated With Sequential Gemcitabine-Docetaxel and Pazopanib Therapy: A Case Report. [PDF]

Cureus
Kurbanova S, Sharobiddinov B, Abdusattorova O, Abdusattorov R.   +3 more
europepmc   +1 more source