Results 11 to 20 of about 1,143,176 (286)

Gene-environment interaction in functional hypothalamic amenorrhea [PDF]

Frontiers in Endocrinology
Functional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea and chronic anovulation in adolescent girls and young women, diagnosed after excluding other organic causes.
Federica Barbagallo, David Bosoni, Valeria Perone, Valeria Perone, Laura Cucinella, Laura Cucinella, Davide Dealberti, Rossella Cannarella, Rossella Cannarella, Aldo E. Calogero, Rossella E. Nappi, Rossella E. Nappi   +11 more
doaj   +2 more sources

Efficient gene–environment interaction testing through bootstrap aggregating [PDF]

Scientific Reports, 2023
Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau, Sara Kress, Tamara Schikowski, Holger Schwender   +3 more
doaj   +2 more sources

Interactive effects between lead-cadmium co-exposure and VEGFA gene polymorphisms on renal dysfunction: a gene–environment interaction study [PDF]

Frontiers in Public Health
BackgroundLead (Pb) and cadmium (Cd) are common persistent environmental pollutants, may cause renal dysfunction following long-term exposure. This study investigated whether vascular endothelial growth factor a (VEGFA) gene polymorphisms modify the ...
Yaotang Deng, Yaotang Deng, Yunman Wen, Weixia Duan, Zhiqiang Zhao, Guoliang Li, Jiazhen Zhou, Le Yang, Jieyi Yang, Yapei Sun, Manyi Qiu, Lili Liu   +11 more
doaj   +2 more sources

Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction [PDF]

BMC Psychology
Mathematical ability is influenced by genes and environment. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability.
Qing Yang, Ximiao Zhang, Liming Zhang, Chen Cheng, Jingjing Zhao   +4 more
doaj   +2 more sources

Gene-environment interaction in the pathophysiology of type 1 diabetes [PDF]

Frontiers in Endocrinology
Type 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities.
Rahul Mittal, Nathanael Camick, Nathanael Camick, Joana R. N. Lemos, Khemraj Hirani   +4 more
doaj   +2 more sources

Gene-environment interaction analysis of school quality and educational inequality [PDF]

npj Science of Learning
We study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and ...
Kim Stienstra, Antonie Knigge, Ineke Maas   +2 more
doaj   +2 more sources

The Familial Clustering of Age at Menarche in Extended Twin Families [PDF]

, 2007
The timing of puberty is complex, possibly involving many genetic factors that may interact with environmental influences. Familial resemblance for age at menarche was studied in a sample of 4,995 female twins, 1,296 sisters, 2,946 mothers and 635 female
A Must, A Pickles, B Towne, CL Sisk, DB Pillemer, DI Boomsma, Dorret I. Boomsma, DS Falconer, DZ Loesch, EB Greif, FJP Ebling, FL Schmidt, G Willemsen, G Wyshak, J Kaprio, JH Stubbe, JL Jinks, JM Meyer, JM Vink, JR Koopmans, L Ibanez, L Zacharias, MR Palmert, SA Treloar, SM Berg van den, SR Ojeda, Stéphanie M. van den Berg   +26 more
core   +15 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

Communications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh, David J. Bernard, Faith Pangilinan, Madison Esposito, Denise Harold, Anne Parle-McDermott, Lawrence C. Brody   +6 more
doaj   +1 more source

Gene–Environment Interactions in Severe Mental Illness [PDF]

Frontiers in Psychiatry, 2014
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
openaire   +3 more sources

Gene-environment interaction in yeast gene expression. [PDF]

PLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +1 more source