The Familial Clustering of Age at Menarche in Extended Twin Families [PDF]
The timing of puberty is complex, possibly involving many genetic factors that may interact with environmental influences. Familial resemblance for age at menarche was studied in a sample of 4,995 female twins, 1,296 sisters, 2,946 mothers and 635 female
A Must+26 more
core +15 more sources
Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua+18 more
doaj +1 more source
Mutual information for testing gene-environment interaction. [PDF]
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj +1 more source
Corrigendum: Gene-environment interaction in the era of precision medicine—filling the potholes rather than starting to build a new road [PDF]
José M. Álvarez-Castro
doaj +2 more sources
Gene-environment interaction in molar-incisor hypomineralization.
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat+22 more
doaj +1 more source
A comprehensive gene–environment interaction analysis in Ovarian Cancer using genome‐wide significant common variants [PDF]
As a follow‐up to genome‐wide association analysis of common variants associated with ovarian carcinoma (cancer), our study considers seven well‐known ovarian cancer risk factors and their interactions with 28 genome‐wide significant common genetic variants.
Elisa V. Bandera+63 more
openaire +6 more sources
Phenotypic heterogeneity and complicated gene–environment interplay in etiology are among the primary factors that hinder the identification of genetic variants associated with cocaine use disorder.To detect novel genetic variants associated with cocaine use disorder, we derived disease traits with reduced phenotypic heterogeneity using cluster ...
Sun, Jiangwen+3 more
openaire +4 more sources
How ambient temperature affects the heading date of foxtail millet (Setaria italica)
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang+8 more
doaj +1 more source
Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj +1 more source
Bayesian semiparametric analysis for two-phase studies of gene-environment interaction [PDF]
The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure to ...
Ahn, Jaeil+3 more
core +1 more source