Results 81 to 90 of about 1,076,570 (292)

Random regression models for detection of gene by environment interaction

open access: yesGenetics Selection Evolution, 2007
Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts ...
Meuwissen Theo HE   +2 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana. [PDF]

open access: yes, 2014
Gene expression varies widely in natural populations, yet the proximate and ultimate causes of this variation are poorly known. Understanding how variation in gene expression affects abiotic stress tolerance, fitness, and adaptation is central to the ...
Des Marais, David L   +7 more
core   +2 more sources

Epigenetic metaphors: an interdisciplinary translation of encoding and decoding

open access: yesNew Genetics and Society, 2019
Looking at the new and often disputed science of epigenetics, we examined the challenges faced by scientists when they communicate scientific research to the public. We focused on the use of metaphors to illustrate notions of epigenetics and genetics. We
Aviad Raz   +2 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Nature-Nurture Debate and Public Policy [PDF]

open access: yes, 2004
The contentious nature-nurture debate in developmental psychology is poised to reach a rapprochement with contemporary concepts of gene-environment interaction, transaction, and fit.
Dodge, Kenneth A.
core   +1 more source

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis [PDF]

open access: yes, 2013
Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Doherty, Michael   +5 more
core   +5 more sources

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Robust Bayesian Variable Selection for Gene-Environment Interactions [PDF]

open access: yes, 2020
Gene-environment (G×E) interactions have important implications to elucidate the etiology of complex diseases beyond the main genetic and environmental effects.
Li, Xiaoxi, Ren, Jie, Wu, Cen, Zhou, Fei
core  

Gene–Environment Interaction in the Era of Precision Medicine – Filling the Potholes Rather Than Starting to Build a New Road

open access: yesFrontiers in Genetics, 2020
Gene–environment interaction is a key part of evolutionary biology, animal, and plant breeding, and a number of health sciences, like epidemiology and precision medicine.
José M. Álvarez-Castro
doaj   +1 more source

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