Results 101 to 110 of about 1,127,640 (282)
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Gene-Environment Interaction in a Conditional NMDAR-Knockout Model of Schizophrenia
Frontiers in Behavioral Neuroscience, 2019 Interactions between genetic and environmental risk factors take center stage in the pathology of schizophrenia. We assessed if the stressor of reduced environmental enrichment applied in adulthood provokes deficits in the positive, negative or cognitive
Alexei M. Bygrave +6 more
doaj +1 more source
Introduction to the Special Issue: The Interplay Between Genetic Factors and the Peer Environment in Explaining Children\u27s Social Adjustment [PDF]
, 2014 Virtually all aspects of human development are subject to both genetic (i.e., heritable) and environmental influences that conjointly shape developmental outcomes through various mechanisms of gene–environment interplay.
Brendgen, Mara
core +1 more source
, 2015 Autism Spectrum Disorder is a complex neurodevelopmental disorder which is often associated with increased anxiety and deficits in cognitive ability.
August, Caren L.
core +2 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
An agent-based simulation framework for complex systems [PDF]
, 2012 In this abstract we present a new approach to the simulation of complex systems as biological interaction networks, chemical reactions, ecosystems, etc.
Benso, Alfredo +4 more
core
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
A platform for the remote conduct of gene-environment interaction studies.
PLoS ONE, 2013 BackgroundGene-environment interaction studies offer the prospect of robust causal inference through both gene identification and instrumental variable approaches. As such they are a major and much needed development.
John Gallacher +7 more
doaj +1 more source
Gene <b>×</b> Environment Interactions in Obesity: The State of the Evidence [PDF]
, 2013 Shafqat Ahmad +2 more
openalex +1 more source