Results 151 to 160 of about 1,150,120 (282)

Gene–environment interaction between APOA5 c.553G>T and pregnancy in hypertriglyceridemia-induced acute pancreatitis

, 2020
Na Pu, Qi Yang, Xiaolei Shi, Weiwei Chen, Xiaoyao Li, Guofu Zhang, Gang Li, Baiqiang Li, Lu Ke, Zhihui Tong, D.N. Cooper, Jian‐Min Chen, Weiqin Li, Jieshou Li   +13 more
openalex   +2 more sources

Gene-Environment Interactions: Paraoxonase (PON1) and Sensitivity to Organophosphate Toxicity [PDF]

, 2006
Lucio G. Costa, Toby B. Cole, Clement E. Furlong   +2 more
openalex   +1 more source

The effects and interaction of soybean maturity gene alleles controlling flowering time, maturity, and adaptation in tropical environments [PDF]

, 2020
Carrie Miranda, Andrew Scaboo, Elroy R. Cober, Nicholas N. Denwar, Kristin Bilyeu   +4 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Summary of the IADR Cariology Research, Craniofacial Biology, and Mineralized Tissue Groups Symposium, Iguaçu Falls, Brazil, June 2012: Gene-environment Interactions and Epigenetics in Oral Diseases: Enamel Formation and its Clinical Impact on Tooth Defects, Caries, and Erosion

, 2013
Adriana Modesto, Ophir D. Klein, Lívia Maria Andaló Tenuta, Raquel F. Gerlach, Alexandre R. Vieira   +4 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gene–Environment Interactions in Irrational Beliefs: The Roles of Childhood Adversity and Multiple Candidate Genes [PDF]

Adina Chiş, Lia-Ecaterina Oltean, Mirela Bîlc, Romana Vulturar, Radu Șoflău, Daniel David, Aurora Szentágotai‐Tătar, Andrei C. Miu   +7 more
openalex   +1 more source

Additional file 2 of Genome-wide associated variants of subclinical atherosclerosis among young people with HIV and gene-environment interactions

, 2023
Jiayu He, Haijiang Lin, Yingying Ding, Xing Liu, Kelin Xu, Xiaoxiao Chen, Weiwei Shen, Sujuan Zhou, Miaochen Wang, Jingjing Xia, Na He   +10 more
openalex   +1 more source