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DC-FusionGNN: A Dual-Channel Framework Integrating Global Self-Attention and Local Topology Learning for Identifying Key Resistance Genes Against <i>Fusarium graminearum</i> Infection in Maize. [PDF]
Dai Y +7 more
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Alterations to the Bronchial Gene-Expression Effects of Tobacco Smoking in People Living With HIV. [PDF]
Lee M +10 more
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Gene expression plasticity under multiple stresses drives higher tolerance to a macrolide in saline and warmer environments. [PDF]
Rescan M, Dachs Rojo M, Borrego CM.
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Analysis of Gene‐Gene Interactions
Current Protocols in Human Genetics, 2017AbstractThe goal of this unit is to introduce epistasis, or gene‐gene interactions, as a significant contributor to the genetic architecture of complex traits, including disease susceptibility. This unit begins with an historical overview of the concept of epistasis and the challenges inherent in the identification of potential gene‐gene interactions ...
Brian S, Cole +4 more
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Assessing Gene-Gene Interactions in Pharmacogenomics
Molecular Diagnosis & Therapy, 2012In pharmacogenomics studies, gene-gene interactions play an important role in characterizing a trait that involves complex pharmacokinetic and pharmacodynamic mechanisms, particularly when each involved feature only demonstrates a minor effect. In addition to the candidate gene approach, genome-wide association studies (GWAS) are widely utilized to ...
Hsien-Yuan, Lane +2 more
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Analysis of Gene‐Gene Interactions
Current Protocols in Human Genetics, 2003AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
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