Results 311 to 320 of about 2,615,001 (338)

Extracting Gene-Gene Interactions Through Curve Fitting

IEEE Transactions on NanoBioscience, 2012
This paper presents a simple and novel curve fitting approach for generating simple gene regulatory subnetworks from time series gene expression data. Microarray experiments simultaneously generate massive data sets and help immensely in the large-scale study of gene expression patterns.
Ranajit, Das, Sushmita, Mitra, C A, Murthy   +2 more
openaire   +2 more sources

Modeling Gene–Gene Interactions in Schizophrenia

2016
Abstract It has been suggested that a substantial portion of the heritable genetic component of schizophrenia risk reflects gene–gene interactions (“epistasis”) rather than simply the cumulative effect of multiple independent genes. However, clinical studies of epistatic interactions require considerable statistical power and place prohibitive ...
E. Von Cheong, Colm M.P. O’Tuathaigh
openaire   +1 more source

Case-Only Design to Measure Gene-Gene Interaction

Epidemiology, 1999
The case-only design is an efficient and valid approach to screening for gene-environment interaction under the assumption of the independence between exposure and genotype in the population. In this paper, we show that the case-only design is also a valid and efficient approach to measuring gene-gene interaction under the assumption that the ...
Q, Yang, M J, Khoury, F, Sun, W D, Flanders   +3 more
openaire   +2 more sources

On the choice of degrees of freedom for testing gene–gene interactions

Statistics in Medicine, 2014
In gene–gene interaction analysis using single nucleotide polymorphism (SNP) data, empty cells arise in the genotype contingency table more frequently than in single SNP association studies. Empty cells lead to unidentifiable regression coefficients in regression model fitting.
openaire   +2 more sources

Integration of the Drug–Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts

Nucleic Acids Research, 2021
Sharon L Freshour, Susanna Kiwala, Kelsy C Cotto   +2 more
exaly  

Gene-Gene Interaction

2013
Elizabeth Galik, Shin Fukudo, Yukari Tanaka, Yori Gidron, Tavis S. Campbell, Jillian A. Johnson, Kristin A. Zernicke, Jennifer Pellowski, Luis I. García, Jason W. Mitchell, Jennifer Toller Erausquin, Rany M. Salem, Laura Rodriguez-Murillo, Ornit Chiba-Falek, Rong Jiang, Rong Jiang, Tavis S. Campbell, Jillian A. Johnson, Kristin A. Zernicke, J. Rick Turner, J. Rick Turner, Bonnie S. LeRoy, Julianne O’Daniel, Jeanette McCarthy, J. Rick Turner, Deidre Pereira, Timothy S. Sannes, Matthew A. Simonson, Jeanette McCarthy, J. Rick Turner, Laura Rodriguez-Murillo, Rany M. Salem, Phil Jones, Ivan Molton, Barbara Resnick, Barbara Resnick, Pearl Ghaemmaghami, Ulrike Ehlert, Yoshiyuki Takimoto, Mustafa al’Absi, Michael James Coons, Janine Sanchez, Michael James Coons, Michael James Coons, Luigi Meneghini, Yori Gidron, Alexandre Morizio, Simon Bacon, Jan R. Oyebode, Jan R. Oyebode, Yori Gidron, Jennifer Cumming, Giles M. Anderson   +52 more
openaire   +1 more source

Gene-environment Interaction in Spherical Equivalent and Myopia: An Evidence-based Review

Ophthalmic Epidemiology, 2022
Xiyan Zhang, Qiao Fan, Fengyun Zhang
exaly  

Gene-Gene Interaction

2020
openaire   +1 more source

Ethnicity-specific Gene–Gene Interaction between IL-13 and IL-4Rα among African Americans with Asthma

American Journal of Respiratory and Critical Care Medicine, 2007
Shweta Choudhry, Kenneth B Beckman, Mariam Naqvi   +2 more
exaly  

Exploration of gene–gene interaction effects using entropy-based methods

European Journal of Human Genetics, 2007
Changzheng Dong, Xun Chu, Li Jin
exaly