Results 61 to 70 of about 16,521,028 (347)

Identifying molecular subgroups of patients with preeclampsia through bioinformatics

Frontiers in Cardiovascular Medicine
Preeclampsia (PE) is a pregnancy-related disorder associated with serious complications. Its molecular mechanisms remain undefined; hence, we aimed to identify molecular subgroups of patients with PE using bioinformatics to aid treatment strategies.
Huijie Zhang, Jianglei Ma, Xueli Gao
doaj   +1 more source

Changing the phenotypes − Epigenetics in ayurveda

Journal of Ayurveda, 2023
Objective: The primary objective is to elaborate the various concepts concerning genetics and epigenetics in Ayurveda. Data Source: The classical Ayurveda texts, along with the commentaries and peer-reviewed articles, were referred.
Priyanka Bhardwaj, Pooja Sabharwal
doaj   +1 more source

Genetic effects on gene expression across human tissues

Nature, 2017
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases.
François Andrew A. Stephane E. Joe R. Yuan Brian Pejman YoS Aguet Brown Castel Davis He Jo Mohammadi Park Pars, François Andrew A. Stephane E. Joe R. Yuan Brian Pejman YoS Aguet Brown Castel Davis He Jo Mohammadi Park Pars, F. Aguet, Andrew A. Brown, Stephane E. Castel, Joe R. Davis, Yuan He, Brian Jo, P. Mohammadi, YoSon Park, P. Parsana, A. Segrè, B. Strober, Zachary Zappala, Beryl B. Ellen T. Kane Katherine H. Monkol Xiao Jared L. Cummings Gelfand Hadley Huang Lek Li Nedzel Nguyen, Beryl B. Cummings, Ellen T. Gelfand, Kane Hadley, Katherine H. Huang, M. Lek, Xiao Li, Jared L. Nedzel, Duyen Y. Nguyen, M. Noble, Timothy J. Sullivan, T. Tukiainen, D. MacArthur, Gad Getz, Anjene Ping Susan A. Roger Nicole C. Helen M. Abhi Jeffer Addington Guan Koester Little Lockhart Moore Rao S, A. Addington, P. Guan, S. Koester, A. Little, N. Lockhart, Helen M. Moore, Abhi Rao, Jeffery P. Struewing, Simona Volpi, Lori E. Richard Marcus Christopher Mark Gene William F. Brigham Hasz Hunter Johns Johnson Kopen Leinweber , L. Brigham, R. Hasz, Marcus Hunter, Christopher Johns, Mark Johnson, G. Kopen, W. F. Leinweber, J. Lonsdale, Alisa McDonald, Bernadette Mestichelli, K. Myer, Brian Roe, Mike Salvatore, Saboor Shad, Jeffrey A. Thomas, Gary Walters, Michael Washington, Joseph Wheeler, J. Bridge, B. Foster, Bryan M. Gillard, E. Karasik, Rachna Kumar, Mark Miklos, M. T. Moser, Scott D. Jewell, Robert G. Montroy, D. Rohrer, Dana R. Valley, Deborah C. Mash, David A. Davis, Leslie Mary E. Philip A. Sobin Barcus Branton, L. Sobin, M. Barcus, P. Branton, Nathan S. Brunilda Olivier Laure Eric R. Diego Ariel D. H Abell Balliu Delaneau Frésard Gamazon Garrido-Mart, Nathan S. Abell, Brunilda Balliu, O. Delaneau, Laure Frésard, E. Gamazon, D. Garrido-Martín, Ariel D. H. Gewirtz, Genna Gliner, Michael J. Gloudemans, Buhm Han, Amy Z. He, F. Hormozdiari, Xin Li, Boxiang Liu, Eun Yong Kang, Ian C. McDowell, H. Ongen, John Palowitch, Christine B. Peterson, G. Quon, S. Ripke, A. Saha, A. A. Shabalin, Tyler C. Shimko, J. Sul, Nicole A. Teran, Emily K. Tsang, Hailei Zhang, Yi-Hui Zhou, C. Bustamante, Nancy J. Cox, R. Guigó, M. Kellis, M. McCarthy, Don Conrad, E. Eskin, Gen Li, A. Nobel, C. Sabatti, Barbara E. Stranger, Xiaoquan Wen, Fred A. Wright, K. Ardlie, E. Dermitzakis, T. Lappalainen, François Kristin G. Beryl B. Ellen T. Gad Kane Robert E. Ka Aguet Ardlie Cummings Gelfand Getz Hadley Handsake, F. Aguet, K. Ardlie, Beryl B. Cummings, Ellen T. Gelfand, Gad Getz, Kane Hadley, R. Handsaker, Katherine H. Huang, Seva Kashin, K. Karczewski, M. Lek, Xiao Li, D. MacArthur, Jared L. Nedzel, Duyen T. Nguyen, M. Noble, A. Segrè, Casandra A. Trowbridge, T. Tukiainen, Nathan S. Brunilda Ruth Omer Alexis Gireesh K. Andrew Chr Abell Balliu Barshir Basha Battle Bogu Brown Brown, Ruth Barshir, Omer Basha, A. Battle, G. Bogu, Andrew Brown, Christopher D. Brown, Lin S. Chen, Colby Chiang, Don Conrad, Nancy J. Cox, Farhan N. Damani, B. Engelhardt, E. Eskin, Pedro G. Ferreira, Laure Frésard, E. Gamazon, D. Garrido-Martín, Ariel D. H. Gewirtz, Genna Gliner, Michael J. Gloudemans, R. Guigó, I. Hall, Buhm Han, F. Hormozdiari, C. Howald, Hae Kyung Im, Brian Jo, Eun Yong Kang, Yungil Kim, Sarah Kim-Hellmuth, Boxiang Liu, S. Mangul, Ian C. McDowell, Jean Monlong, Stephen B Montgomery, Manuel Muñoz-Aguirre, Anne W. Ndungu, Dan L. Nicolae, Meritxell Oliva, N. Panousis, Panagiotis K. Papasaikas, YoSon Park, Anthony J. Payne, J. Quan, F. Reverter, M. Sammeth, Alexandra J. Scott, A. A. Shabalin, Reza Sodaei, M. Stephens, Barbara E. Stranger, Sarah Urbut, M. van de Bunt, Gao Wang, Fred A. Wright, H. Xi, Esti Yeger-Lotem, Judith B. Zaugg, Yi-Hui Zhou, Joshua M. Daniel Joanne Lin S. Melina Kathryn Morgan Jenn Akey Bates Chan Chen Claussnitzer Demanelis Diegel, J. Akey, Daniel Bates, Joanne Chan, M. Claussnitzer, Kathryn Demanelis, Morgan Diegel, J. Doherty, A. Feinberg, Maria S. Fernando, J. Halow, Kasper D. Hansen, E. Haugen, P. Hickey, Lei Hou, F. Jasmine, Ruiqi Jian, Lihua Jiang, Audra K. Johnson, R. Kaul, M. Kellis, M. Kibriya, Kristen Lee, Jin Billy Li, Qin Li, Xiao Li, Jessica Lin, Shin Lin, Sandra Linder, C. Linke, Yaping Liu, Matthew T. Maurano, B. Molinie, Stephen B Montgomery, Jemma Nelson, Fidencio J. Neri, Yongjin Park, B. Pierce, Nicola J. Rinaldi, L. Rizzardi, R. Sandstrom, Andrew Skol, Kevin S. Smith, Michael P. Snyder, J. Stamatoyannopoulos, Hua Tang, L. Wang, M. Wang, Nicholas Van Wittenberghe, Fan Wu, Rui Zhang, C. Nierras, Philip A. Latarsha J. Ping Helen M. Abhi Jimmie B. Branton Carithers Guan Moore Rao Vaught, P. Branton, Latarsha J. Carithers, P. Guan, Helen M. Moore, Abhi Rao, J. Vaught, Sarah E. Nicole C. Casey Jeffery P. Simona Gould Lockart Martin Struewing Volpi, Sarah E. Gould, Nicole C. Lockart, Casey Martin, Jeffery P. Struewing, Simona Volpi, Anjene M. Susan E. Addington Koester, A. Addington, S. Koester, A. Little, Lori E. Richard Marcus Christopher Mark Gene William F. Brigham Hasz Hunter Johns Johnson Kopen Leinweber , L. Brigham, Mark Johnson, Brian Roe, Gary Walters, Michael Washington, Jason Barbara A. Bryan M. Ellen Rachna Mark Michael T. Bridge Foster Gillard Karasik Kumar Miklos Moser, Scott D. Robert G. Daniel C. Dana R. Jewell Montroy Rohrer Valley, Scott D. Jewell, Robert G. Montroy, D. Rohrer, Dana R. Valley, David A. Deborah C. Davis Mash, David A. Davis, Deborah C. Mash, Anita H. Anna M. David E. Nancy V. Jeffrey A. Negin Karn Undale Smith Tabor Roche McLean Vatanian Robinson , Anita H. Undale, Anna M. Smith, D. Tabor, Nancy V. Roche, J. McLean, Negin Vatanian, Karna L. Robinson, L. Sobin, M. Barcus, Kimberly M. Valentino, L. Qi, Steven Hunter, P. Hariharan, Shilpi Singh, K. S. Um, Takunda Matose, M. Tomaszewski, Laura K. Maghboeba Laura A. Heather M. Barker Mosavel Siminoff Traino, Laura K. Barker, M. Mosavel, L. Siminoff, H. Traino, Paul Thomas Magali Dan Kieron Stephen J. Daniel R. Flicek Juettemann Ruffier Sheppard Taylor Trevanio, Paul Flicek, Thomas Juettemann, Magali Ruffier, Daniel Sheppard, K. Taylor, S. Trevanion, D. Zerbino, Brian Mary Maximilian W. James Christopher M. Benedict K Craft Goldman Haeussler Kent Lee Paten Rosenbloom , Brian Craft, M. Goldman, M. Haeussler, W. Kent, Christopher M. Lee, B. Paten, K. Rosenbloom, John Vivian, Jingchun Zhu   +324 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Extension of the Temporary Assistance for Needy Families (TANF) Block Grant in the Consolidated Appropriations Act: In Brief [PDF]

, 2017
[Excerpt] The pending FY2017 Consolidated Appropriations Act (the proposed House amendment to the Senate amendment to H.R. 244) would extend funding for the Temporary Assistance for Needy Families (TANF) block grant for the remainder of FY2017 and for ...
Falk, Gene
core   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Temporary Assistance for Needy Families (TANF): Issues for the 110th Congress [PDF]

, 2007
Enactment of the Deficit Reduction Act of 2005 (DRA, P.L. 109-171) ended more than four years of congressional debate on “reauthorizing” the block grant of Temporary Assistance for Needy Families (TANF).
Falk, Gene
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Ultrasound-Responsive Materials for Drug/Gene Delivery

Frontiers in Pharmacology, 2020
Ultrasound is one of the most commonly used methods in the diagnosis and therapy of diseases due to its safety, deep penetration into tissue, and non-invasive nature.
Xiaowen Cai, Yuan Jiang, Mei Lin, Jiyong Zhang, Huanhuan Guo, Fanwen Yang, Wingnang Leung, Chuanshan Xu   +7 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source