Results 71 to 80 of about 8,938,319 (306)

Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women. [PDF]

open access: yes, 2015
Bacterial vaginosis (BV) is a common vaginal syndrome associated with altered microflora that increases the risk of preterm delivery and acquisition of sexually transmitted diseases.
Bigham, Abigail W   +13 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The history of Drosophila studies: steps in the development of genetics

open access: yesВавиловский журнал генетики и селекции, 2015
Experimental genetic studies of Drosophila were initiated by T.H. Morgan in 1910, when he discovered the sex-linked white-eyed mutation, white. This discovery commenced the transformation of Mendel’s “hereditary factors” to more specific but no less ...
N. N. Yurchenko   +2 more
doaj   +1 more source

Extension of the Temporary Assistance for Needy Families (TANF) Block Grant in the Consolidated Appropriations Act: In Brief [PDF]

open access: yes, 2017
[Excerpt] The pending FY2017 Consolidated Appropriations Act (the proposed House amendment to the Senate amendment to H.R. 244) would extend funding for the Temporary Assistance for Needy Families (TANF) block grant for the remainder of FY2017 and for ...
Falk, Gene
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus

open access: yesПроблемы особо опасных инфекций, 2015
The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov   +8 more
doaj   +1 more source

The cumulative effects of known susceptibility variants to predict primary biliary cirrhosis risk. [PDF]

open access: yes, 2015
Multiple genetic variants influence the risk for development of primary biliary cirrhosis (PBC). To explore the cumulative effects of known susceptibility loci on risk, we utilized a weighted genetic risk score (wGRS) to evaluate whether genetic ...
Bian, Z   +10 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

ACUTE CEREBROVASCULAR EVENTS IN PATIENTS WITH ARTERIAL HYPERTENSION: MOLECULAR GENETIC ASPECTS

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study association between stroke and gene polymorphism of angeotensin converting enzyme (ACE), angeotensin II type 1 receptor (ATR1), apolipoprotein СIII (APO CIII), apoproteine Е (APO E), methylentetrahydrofolate reductase (MTHFR), fibrinogen ...
M. A. Karpenko   +4 more
doaj   +1 more source

Temporary Assistance for Needy Families (TANF): Issues for the 110th Congress [PDF]

open access: yes, 2007
Enactment of the Deficit Reduction Act of 2005 (DRA, P.L. 109-171) ended more than four years of congressional debate on “reauthorizing” the block grant of Temporary Assistance for Needy Families (TANF).
Falk, Gene
core   +1 more source

Home - About - Disclaimer - Privacy