Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women. [PDF]
Bacterial vaginosis (BV) is a common vaginal syndrome associated with altered microflora that increases the risk of preterm delivery and acquisition of sexually transmitted diseases.
Bigham, Abigail W +13 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The history of Drosophila studies: steps in the development of genetics
Experimental genetic studies of Drosophila were initiated by T.H. Morgan in 1910, when he discovered the sex-linked white-eyed mutation, white. This discovery commenced the transformation of Mendel’s “hereditary factors” to more specific but no less ...
N. N. Yurchenko +2 more
doaj +1 more source
Extension of the Temporary Assistance for Needy Families (TANF) Block Grant in the Consolidated Appropriations Act: In Brief [PDF]
[Excerpt] The pending FY2017 Consolidated Appropriations Act (the proposed House amendment to the Senate amendment to H.R. 244) would extend funding for the Temporary Assistance for Needy Families (TANF) block grant for the remainder of FY2017 and for ...
Falk, Gene
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus
The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov +8 more
doaj +1 more source
The cumulative effects of known susceptibility variants to predict primary biliary cirrhosis risk. [PDF]
Multiple genetic variants influence the risk for development of primary biliary cirrhosis (PBC). To explore the cumulative effects of known susceptibility loci on risk, we utilized a weighted genetic risk score (wGRS) to evaluate whether genetic ...
Bian, Z +10 more
core +2 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
ACUTE CEREBROVASCULAR EVENTS IN PATIENTS WITH ARTERIAL HYPERTENSION: MOLECULAR GENETIC ASPECTS
Aim. To study association between stroke and gene polymorphism of angeotensin converting enzyme (ACE), angeotensin II type 1 receptor (ATR1), apolipoprotein СIII (APO CIII), apoproteine Е (APO E), methylentetrahydrofolate reductase (MTHFR), fibrinogen ...
M. A. Karpenko +4 more
doaj +1 more source
Temporary Assistance for Needy Families (TANF): Issues for the 110th Congress [PDF]
Enactment of the Deficit Reduction Act of 2005 (DRA, P.L. 109-171) ended more than four years of congressional debate on “reauthorizing” the block grant of Temporary Assistance for Needy Families (TANF).
Falk, Gene
core +1 more source

