Results 41 to 50 of about 6,617,997 (307)

Stria Gravidarum Is Genetic But Not Related With Collagen Gene Polymorphism [PDF]

, 2013
BACKGROUND: Striae Gravidarum (SG) is a common problem that complicates the pregnancies. We aimed to evaluate the possible etiologic factors of SG and the possible importance of collagen polymorphism on SG.
Gungor, Cakir A. N., Gencer, M., Silan, F., Uysal, A., Isik, S., Oguz, S., Uludag, A.   +6 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis

Frontiers in Nutrition
BackgroundGut microbiota (GM) and metabolic alterations play pivotal roles in lung cancer (LC) development and host genetic variations are known to contribute to LC susceptibility by modulating the GM. However, the causal links among GM, metabolite, host
Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong   +8 more
doaj   +1 more source

Bayesian mixture modeling of gene‐environment and gene‐gene interactions [PDF]

Genetic Epidemiology, 2009
AbstractWith the advent of rapid and relatively cheap genotyping technologies there is now the opportunity to attempt to identify gene‐environment and gene‐gene interactions when the number of genes and environmental factors is potentially large. Unfortunately the dimensionality of the parameter space leads to a computational explosion in the number of
Wakefield, Jon, De Vocht, Frank, Hung, Rayjean J.   +2 more
openaire   +5 more sources

Enterokinase deficiency associated with novel TMPRSS15 gene mutations: a case report

Frontiers in Pediatrics
BackgroundEnterokinase deficiency (EKD,OMIM #226200) is a rare autosomal recessive genetic disorder caused by mutations in transmembrane protease serine 15 (TMPRSS15). Herein, we report a case of EKD in a patient with novel compound heterozygous TMPRSS15
Yunxi Li, Ruijuan Li, Yanyan Pan, Weiran Zhou, Xingcui Wang, Linlin Dong, Xuemei Liu, Hongxia Zhang   +7 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Differences in Gene Expression between Sonoporation in Tumor and in Muscle

, 2010
Background Ultrasound (US) is a novel and effective tool for the local delivery of genes into target tissues. US can temporarily change the permeability of a cell membrane and thus enhance the delivery of naked DNA into cells.
TSAI, KUN-CHE;LIAO, ZHE-KANG;LIN, WIN-LI;SHIEH, MING-JIUM;HWAN,G LIH-HWA;CHEN, WEN-SHIANG, 蔡坤哲;廖哲康;林文澧;謝銘鈞;黃麗華;陳文翔   +1 more
core   +1 more source

Marfan syndrome: insights from animal models

Frontiers in Genetics
Marfan syndrome (MFS) is an inherited disorder that affects the connective tissues and mainly presents in the bones, eyes, and cardiovascular system, etc. Aortic pathology is the leading cause of death in patients with Marfan syndrome.
Yuanyuan Jiang, Ping Jia, Xiaoying Feng, Dingding Zhang   +3 more
doaj   +1 more source

The comparative assessment of single dose versus co-administration of salinomycin and MK-2206 on viability, apoptosis, and gene expression of human prostate cancer cells

Journal of Current Biomedical Reports, 2023
Globally, the most prevalent medical condition affecting males is identified as prostate cancer (PCa). The aim of the present study was the comparative assessment of single dose versus co-administration of salinomycin and MK-2206 on several laboratory ...
Mohamadreza Savaee, Ali Bakhshi, Mehran Dehghanian, Ghafour Yarahmadi, Fatemeh Yaghoubi, Fatemeh Pourrajab   +5 more
doaj   +1 more source