Results 31 to 40 of about 8,938,319 (306)
To the Medical Research Council, currently enjoying the warmth of celebrations marking the 50th anniversary of Crick and Watson's discovery of the double helix at an MRC laboratory, last week's report by the House of Commons science and technology committee must have felt like a bucket of ice cold water.
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Gene–Gene and Gene–Environment Interactions in Apolipoprotein L1 Gene-Associated Nephropathy [PDF]
Molecular genetics have revolutionized the understanding of susceptibility to the broad spectrum of kidney diseases with light microscopic appearance of FSGS, particularly in populations with recent African ancestry. These disorders include idiopathic FSGS, HIV-associated nephropathy, severe lupus nephritis, sickle cell nephropathy, and the primary ...
Barry I, Freedman, Karl, Skorecki
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Identifying molecular subgroups of patients with preeclampsia through bioinformatics
Preeclampsia (PE) is a pregnancy-related disorder associated with serious complications. Its molecular mechanisms remain undefined; hence, we aimed to identify molecular subgroups of patients with PE using bioinformatics to aid treatment strategies.
Huijie Zhang, Jianglei Ma, Xueli Gao
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As a common influencing factor in the environment, temperature greatly influences the fish that live in the water all their life. The essential economic fish Chinese tongue sole (Cynoglossus semilaevis), a benthic fish, will experience both physiological
Yue Wang +9 more
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A Lost Dream: Worker Control at Rath Packing [PDF]
[Excerpted from Introduction by Gene Daniels] The story of Rath Packing Company of Waterloo, Iowa, is alternately a model of the American Dream and the story of a dream turned nightmare.
Daniels, Gene +2 more
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ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
What School Principals Need to Know About Curriculum and Instruction [PDF]
Looks at what school leaders need to know about instructional practices, organizing a school for greater student learning, supporting teacher development, and balancing school improvement with non-instructional issues and ...
Gene Bottoms
core
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Bayesian mixture modeling of gene‐environment and gene‐gene interactions [PDF]
AbstractWith the advent of rapid and relatively cheap genotyping technologies there is now the opportunity to attempt to identify gene‐environment and gene‐gene interactions when the number of genes and environmental factors is potentially large. Unfortunately the dimensionality of the parameter space leads to a computational explosion in the number of
Wakefield, Jon +2 more
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