Results 161 to 170 of about 8,130,594 (350)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Prognostic Significance of Actinin-4 Protein Expression and Gene Amplification in Endometrial Carcinoma. [PDF]

J Obstet Gynaecol Res
Xiang L, Naito Y, Toyoshima M, Terasaki M, Yamamoto A, Shimizu A, Suzuki S, Honda K.   +7 more
europepmc   +1 more source

Fluorometric Detection of SARS-CoV-2 Single-Nucleotide Variant L452R Using Ligation-Based Isothermal Gene Amplification. [PDF]

Bioengineering (Basel), 2023
Kyung K, Ku J, Cho E, Ryu J, Woo J, Jung W, Kim DE.   +6 more
europepmc   +1 more source

Amplification and molecular cloning of the inosine 5-monophosphate dehydrogenase gene of Leishmania donovani and Trypanosoma brucei

, 1992
Keith E. Wilson
openalex   +1 more source

Modified 3′-End Amplification PCR for Gene Expression Analysis in Single Cells [PDF]

, 2003
Thomas Heams, Jean-Jacques Kupiec
openalex   +1 more source

A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

Cell, 2014
M. Tanenbaum, Luke A. Gilbert, Lei S. Qi, J. Weissman, R. Vale   +4 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ACTN4 Gene Amplification and Actinin-4 Protein Expression for Osimertinib Efficacy in EGFR-Mutant NSCLC. [PDF]

Cancer Sci
Tozuka T, Noro R, Naito Y, Miura N, Kunugi S, Honda K, Seike M.   +6 more
europepmc   +1 more source

Molecular Serotyping ofKlebsiellaSpecies Isolates by Restriction of the Amplified Capsular Antigen Gene Cluster

, 2004
Sylvain Brisse, Sylvie Issenhuth-Jeanjean, Patrick A. D. Grimont   +2 more
openalex   +2 more sources

Activating HER2 mutations in HER2 gene amplification negative breast cancer.

Cancer Discovery, 2013
R. Bose, Shyam M. Kavuri, Adam C. Searleman, W. Shen, D. Shen, D. Koboldt, J. Monsey, Nicholas J. Goel, Adam B Aronson, Shunqiang Li, Cynthia X. Ma, L. Ding, E. Mardis, M. Ellis   +13 more
semanticscholar   +1 more source