Results 181 to 190 of about 8,013,600 (393)

Gene amplification mutations originate prior to selective stress in Acinetobacter baylyi. [PDF]

G3 (Bethesda), 2023
Herrmann JA, Koprowska A, Winters TJ, Villanueva N, Nikityuk VD, Pek F, Reis EM, Dominguez CZ, Davis D, McPherson E, Rocco SR, Recendez C, Difuntorum SM, Faeth K, Lopez MD, Awwad HM, Ghobashy RA, Cappiello L, Neidle EL, Quiñones-Soto S, Reams AB.   +20 more
europepmc   +1 more source

Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results from amplification of an esterase gene [PDF]

, 1988
L. M. Field, A. L. Devonshire, Brian Forde   +2 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Gene amplifications associated with the development of hormone- resistant prostate cancer [PDF]

, 2003
Purpose: Hormone resistance remains a significant clinical problem in prostate cancer with few therapeutic options. Research into mechanisms of hormone resistance is essential.
Bartlett, J.M.S., Edwards, J., Krishnan, S., Witton, C.J.   +3 more
core  

Fluorometric Detection of SARS-CoV-2 Single-Nucleotide Variant L452R Using Ligation-Based Isothermal Gene Amplification. [PDF]

Bioengineering (Basel), 2023
Kyung K, Ku J, Cho E, Ryu J, Woo J, Jung W, Kim DE.   +6 more
europepmc   +1 more source

Identification of genes from pattern formation, tyrosine kinase, and potassium channel families by DNA amplification.

, 1989
Alexander Kamb, Michael P. Weir, Bernardo Rudy, Harold Varmus, Cynthia Kenyon   +4 more
openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Amplification enhancers and replication origins in the autosomal chorion gene cluster of Drosophila. [PDF]

, 1989
Christos Delidakis, Fotis C. Kafatos
openalex   +1 more source

Decoding multicellular interaction networks–a new horizon in tumor microenvironment research

Molecular Oncology, Volume 19, Issue 4, Page 957-960, April 2025.
Cells in the tumor microenvironment influence tumor establishment and progression through an elaborate array of cellular interactions. Integrating transcriptomic, spatial, and intercellular crosstalk data at single‐cell resolution unveil complex, functionally distinct multicellular circuits.
Roi Balaban, Merav Cohen
wiley   +1 more source

Investigating the mechanisms of glyphosate resistance in goosegrass (Eleusine indica) population from South China

Journal of Integrative Agriculture, 2015
Glyphosate has been used worldwide for nearly 40 years, and 30 types of resistant weeds have been reported. Glyphosate is mass-produced and widely used in China, but few studies and reports on glyphosate-resistant weeds and resistance mechanisms exist ...
Chun ZHANG, Li FENG, Ting-ting HE, Cai-hong YANG, Guo-qi CHEN, Xing-shan TIAN   +5 more
doaj