Results 231 to 240 of about 8,013,600 (393)

Human myeloma cells acquire resistance to difluoromethylornithine by amplification of ornithine decarboxylase gene [PDF]

, 1987
Pekka Leinonen, Leena Alhonen‐Hongisto, Riku Laine, Olli A. Jänne, Juhani Jänne   +4 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Template switching during DNA replication is a prevalent source of adaptive gene amplification. [PDF]

Elife
Chuong JN, Ben Nun N, Suresh I, Matthews JC, De T, Avecilla G, Abdul-Rahman F, Brandt N, Ram Y, Gresham D.   +9 more
europepmc   +1 more source

Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae. [PDF]

Antimicrob Agents Chemother, 2022
Yamada T, Yaguchi T, Maeda M, Alshahni MM, Salamin K, Guenova E, Feuermann M, Monod M.   +7 more
europepmc   +1 more source

Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.

, 1986
S. Fukushige, Keiko Matsubara, Megumi Yoshida, Makoto Sasaki, Tomonari Suzuki, Kentaro Semba, K Toyoshima, Tadashi Yamamoto   +7 more
openalex   +1 more source

Tetracycline resistance transposon Tn1721: recA-dependent gene amplification and expression of tetracycline resistance [PDF]

, 1981
K Wiebauer, S Schraml, Stuart W. Shales, R. Schmitt   +3 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Plasmon-Driven Gold Nanopillar Multiarrayed Gene Amplification Methodology for the High-Throughput Discrimination of Pathogens. [PDF]

Adv Sci (Weinh)
Seo SE, Kim KH, Kim SJ, Ko KC, Kim WK, Lee KG, Kwon OS.   +6 more
europepmc   +1 more source

High cyclin E1 protein, but not gene amplification, is prognostic for basal-like breast cancer. [PDF]

J Pathol Clin Res, 2022
Aziz D, Lee C, Chin V, Fernandez KJ, Phan Z, kConFab Investigators, AOCS Study Group, Waring P, Caldon CE.   +8 more
europepmc   +1 more source

Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-rasgene and localization of homologous sequences to mouse chromosome 6 [PDF]

, 1984
Donna L. George, Alan F. Scott, Bérengère de Martinville, Uta Francke   +3 more
openalex   +1 more source