Results 111 to 120 of about 7,510,778 (382)

High-throughput sequencing data and the impact of plant gene annotation quality

Journal of Experimental Botany, 2018
The use of draft genomes of different species and re-sequencing of accessions and populations are now common tools for plant biology research. The de novo assembled draft genomes make it possible to identify pivotal divergence points in the plant lineage
Aleksia Vaattovaara, J. Leppälä, J. Salojärvi, Michael Wrzaczek   +3 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On gene ontology and function annotation [PDF]

Bioinformation, 2006
The effort of function annotation does not merely involve associating a gene with some structured vocabulary that describes action. Rather the details of the actions, the components of the actions, the larger context of the actions are important issues that are of direct relevance, because they help understand the biological system to which the gene ...
openaire   +2 more sources

Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum [PDF]

, 2016
BACKGROUND: Stagonospora nodorum, a fungal ascomycete in the class dothideomycetes, is a damaging pathogen of wheat. It is a model for necrotrophic fungi that cause necrotic symptoms via the interaction of multiple effector proteins with cultivar ...
Bringans, Scott, Casey, Tammy, Hane, James, Lipscombe, Richard J, Oliver, Richard Peter, Solomon, Peter S, Tan, Kar-Chun   +6 more
core   +1 more source

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

Nucleic Acids Res., 2016
The PANTHER database (Protein ANalysis THrough Evolutionary Relationships, http://pantherdb.org) contains comprehensive information on the evolution and function of protein-coding genes from 104 completely sequenced genomes.
H. Mi, Xiaosong Huang, A. Muruganujan, Haiming Tang, Caitlin Mills, Diane Kang, P. Thomas   +6 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Re-annotation of genome microbial CoDing-Sequences: finding new genes and inaccurately annotated genes [PDF]

BMC Bioinformatics, 2002
Analysis of any newly sequenced bacterial genome starts with the identification of protein-coding genes. Despite the accumulation of multiple complete genome sequences, which provide useful comparisons with close relatives among other organisms during the annotation process, accurate gene prediction remains quite difficult.
Danchin Antoine, Bocs Stéphanie, Médigue Claudine   +2 more
openaire   +3 more sources

SynGAP: a synteny-based toolkit for gene structure annotation polishing

Genome Biology
Genome sequencing has become a routine task for biologists, but the challenge of gene structure annotation persists, impeding accurate genomic and genetic research.
Fengqi Wu, Yingxiao Mai, Chengjie Chen, Rui Xia   +3 more
doaj   +1 more source

GenColors: Annotation and comparative genomics made easy [PDF]

, 2009
GenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al., _Bioinformatics_ 2005; Romualdi et al., _Methods Mol.
Alessandro Romualdi, Gernot Gloeckner, Juergen Suehnel, Marius Felder, Matthias Platzer   +4 more
core   +2 more sources

Increased alignment sensitivity improves the usage of genome alignments for comparative gene annotation

Nucleic Acids Research, 2017
Genome alignments provide a powerful basis to transfer gene annotations from a well-annotated reference genome to many other aligned genomes. The completeness of these annotations crucially depends on the sensitivity of the underlying genome alignment ...
Virag Sharma, M. Hiller
semanticscholar   +1 more source