Results 131 to 140 of about 7,510,778 (382)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]

open access: yes, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S.   +4 more
core   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

COLOMBOS v2.0 : an ever expanding collection of bacterial expression compendia [PDF]

open access: yes, 2013
The COLOMBOS database (http://www.colombos.net) features comprehensive organism-specific cross-platform gene expression compendia of several bacterial model organisms and is supported by a fully interactive web portal and an extensive web API.
Bianco, Luca   +11 more
core   +1 more source

Identification of Hub Genes and Functional Annotation of Glaucoma Using Bioinformatic Analysis [PDF]

open access: gold, 2023
P. Russell Aaron   +4 more
openalex   +1 more source

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow

open access: yesNature Communications, 2016
Complete annotation of the human genome is indispensable for medical research. The GENCODE consortium strives to provide this, augmenting computational and experimental evidence with manual annotation.
James C. Wright   +7 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Visualizing Gene Ontology annotations

open access: yes, 2016
to appear in the forthcoming book "The Gene Ontology Handbook" (Springer Humana, ISBN 978-1-4939-3741-7)
Supek, Fran, Škunca, Nives
openaire   +2 more sources

Genome-wide association for grain yield under semi-arid conditions in historical wheat cultivars from Pakistan

open access: yesFrontiers in Plant Science, 2015
Genome-wide association studies (GWAS) were undertaken to identify SNP markers associated with yield and yield-related traits in 123 Pakistani historical wheat cultivars evaluated during 2011-2014 seasons under semi-arid field conditions.
Qurat-ul eAin   +10 more
doaj   +1 more source

A biophysical approach to large-scale protein-DNA binding data [PDF]

open access: yes, 2008
About this book * Cutting-edge genome analysis methods from leading bioinformaticians An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens ...
Manke, T., Roider, H., Vingron, M.
core   +1 more source

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